Aglycone flavonoids of Centaurea tougourensis from Algeria

Nacer, A.; Bernard, Aurélie; Boustié, Joël; Touzani, Rachid; Kabouche, Zahia

doi:10.1007/s10600-006-0088-4

Cited by 26 publications

(11 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some of them show antimicrobial activity (Karioti et al, 2001;ugur et al, 2009). Metabolites are predominantly sesquiterpene lactones (Tarasov et al, 1975;Koukoulitsa et al, 2005;Karamenderes et al, 2007), but also flavonoids (Zapesochnaya et al, 1978;Nacer et al, 2006), essential oils (Altintas et al, 2004) and phenols (Bubenchikov et al, 1992). Many phytochemical studies have been published over the last decade but only very few address explicitly systematic questions (but see Yildirim et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Notas taxonómicas y nomenclaturales en Centaurea: propuesta de clasificación, descripción de secciones y subsecciones nuevas, y lista de especies de una sección Centaurea redefinida

et al. 2014

View full text Add to dashboard Cite

En este trabajo presentamos los resultados de nuestras investigaciones de larga fecha en el género Centaurea. La primera parte del trabajo trata de la clasificación del género, que proponemos dividir en tres subgéneros: subgénero Centaurea, subgénero Cyanus y subgénero Lopholoma. La segunda parte es una recopilación de las especies de la redefinida sección Centaurea, que incluye las antiguas secciones Acrolophus (sect. Centaurea s. str.), Phalolepis y Willkommia, junto con consideraciones geográficas, ecológicas y cariológicas. Por último, proponemos nuevas secciones, subsecciones y combinaciones para correlacionar nomenclatura y clasificación: proponemos una nueva (sect. Acrocentron subsect. Chamaecyanus) en el subgénero Lopholoma; se describen tres secciones nuevas (sects. Akamantis, Cnicus y Hyerapolitanae) en el subgénero Centaurea; dos subsecciones (subsects. Phalolepis and Willkommia) en la sección Centaurea; y tres subsecciones (subsects. Exarata, Jacea y Subtilis) en la sección Phrygia.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Ellis, 1999). Some species are used as medicinals, especially in folk medicine, because of its secondary compounds (Nacer et al, 2006;Akkol et al, 2009). The sesquiterpene lactone cnicin, found in Centaurea benedicta (the name of the compound derives from its former name Cnicus benedictus L.) and other species of sect.…”

Section: Subgenus Centaureamentioning

confidence: 99%

Notas taxonómicas y nomenclaturales en Centaurea: propuesta de clasificación, descripción de secciones y subsecciones nuevas, y lista de especies de una sección Centaurea redefinida

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Centaurea species have been the object of various phytochemical studies, with a diversity of bioactive phytochemicals and prevalence of flavonoids 2 , flavonoid aglycones 3 , lignans 4 , sesquiterpene lactones 5 , essential oils 6 , alkaloids 7 and other biologically active constituents. Some species of the genus Centaurea have been used as medicinal plants in folk medicine for their uses in gastrointestinal 8 and inflammatory disorders 9 , cytotoxic activity 4,10 , in addition to the anti-microbial 11,12 and antioxidant activities 13 .…”

Section: Genusmentioning

confidence: 99%

Phenolic Compounds and Hepatoprotective Activity of Centaurea aegyptiaca L. on Carbon Tetrachloride-induced Hepatotoxicity in Rats

Senosy

Kamal

El‐Toumy

et al. 2018

Journal of Advanced Pharmacy Research

View full text Add to dashboard Cite

Objectives: This study aimed to isolate phenolic compounds from the 70% aqueous methanol extract of the aerial parts (leaves, flowers and stems) of Centaurea aegyptiaca , evaluate in-vivo hepatoprotective activity and determine total phenolic and total flavonoid contents. Methods: 70% aqueous methanol extract of the aerial parts subjected to different chromatographic separation techniques. The identities of the isolated compounds were established on the basis of their spectral data and comparing with previously reported data. The crude extract was evaluated for invivo hepatoprotective activity on CCl4-induced hepatotoxicity in rats. Total phenolic and total flavonoid contents of the aqueous methanol extract were determined using Folin-Ciocalteu and aluminum chloride colorimetric methods, respectively. Results: The aqueous methanol extract of the aerial parts of Centaurea aegyptiaca afforded seven compounds. A phenolic acid ester; protochatechuic acid methyl ester (1) along with six known flavonoids; apigenin-6-C-β-D-glucopyranoside (isovitexin) (2), apigenin-8-C-β-D-glucopyranoside (vitexin) (3), quercetin-3-O--Dglucopyranoside (isoquercetin) (4), apigenin (5), 3-O-methylquercetin (6) and quercetin (7). Administration of the extract at doses of 100 and 200 mg/kg b.wt showed a hepatoprotective activity similar to that of the standard drug; silymarin at a dose of 25 mg/kg b.wt. Comparative histopathological study of liver exhibited moderate changes in liver histoarchitecture when compared to the CCl4 group. The methanolic extract showed high concentration of phenolic and flavonoid contents. Conclusion: The aqueous methanol extract of the aerial parts of C. aegyptiaca afforded seven phenolic compounds for the first time from this species, with promising in-vivo hepatoprotective activity.

show abstract

“…Centaurea L. is a large genus which comprised of several species (spp. ), many of which are used in folk medicine (Nacer et al, 2006). The presence of 400 to 700 species in this genus makes it one of the biggest genera of the family (Dittrich, 1977;Gracia-Jacas et al, 2001;Wagenitiz and Hellwig, 1996).…”

Section: Introductionmentioning

confidence: 99%

In vitro regeneration, flowering, and cell culture of Centaurea species

Alaiwi¹

2012

Afr. J. Biotechnol.

View full text Add to dashboard Cite

This study was conducted to establish a protocol for in vitro flowering of Centaurea cyanus and cell cultures of Centaurea montana. In four weeks, 50 to 60 adventitious shoots developed on leaf explants cultured in MS medium supplemented with 2.0 mg/L benzylaminopurine (BAP) and 0.1 mg/L indole-3acetic acid (IAA). In vitro flowering and seed set occurred in C. cyanus when the shoots were incubated on MS basal medium supplemented with B5 vitamins, 100 mg/L myo-inositol and 30 g/L sucrose for 4 weeks under 16 h photoperiod. Young leaves of C. montana cultured on MS medium supplemented with 1.0 to 6.0 mg/L 2, 4-dichloroxypenoxyacetic acid (2, 4-D) alone or in combination with 0.5 mg/L BAP generated callus. Liquid MS medium containing 2.0 mg/L 2, 4-D produced greater fresh weight (FW), dry weight (DW) and packed cell volume (PCV) compared to MS medium with 1 mg/L 2, 4-D in a 30 day culture cycle. The results indicate that MS medium modified with appropriate phytohormones can be used to achieve efficient shoot regeneration and in vitro flowering of C. cyanus and cell cultures of C. montana.

show abstract

Aglycone flavonoids of Centaurea tougourensis from Algeria

Cited by 26 publications

References 10 publications

Notas taxonómicas y nomenclaturales en <em>Centaurea</em>: propuesta de clasificación, descripción de secciones y subsecciones nuevas, y lista de especies de una sección <em>Centaurea</em> redefinida

Notas taxonómicas y nomenclaturales en <em>Centaurea</em>: propuesta de clasificación, descripción de secciones y subsecciones nuevas, y lista de especies de una sección <em>Centaurea</em> redefinida

Phenolic Compounds and Hepatoprotective Activity of Centaurea aegyptiaca L. on Carbon Tetrachloride-induced Hepatotoxicity in Rats

In vitro regeneration, flowering, and cell culture of Centaurea species

Contact Info

Product

Resources

About