“…The first example was described by Walsh and Montgomery (1947), and the other by Mary Pickles (1948). A naturally occurring antibody anti-S was found in the serum of a patient by Coombs et al (1951) and in the blood of a donor by Vogel and Rosenfield (see Race and Sanger, 1950). In three cases the formation of anti-S was the result of multiple transfusions (Cutbush and Mollison, 1949;Race et al, 1949;Collins et al, 1950).…”