Age-Related Differences of Risk Profile and Angiographic Findings in Patients with Coronary Heart Disease

AGE-Related Differences of Novel Atherosclerotic Risk Factors and Angiographic Profile Among Gujarati Acute Coronary Syndrome Patients

“…Although our study demonstrated a stronger association between smoking, tobacco chewing, hyperlipidemia, and obesity and ACS in younger patients, hypertesnion and positive family history of premature CAD were the only discriminatory risk factors between the two age groups. This is in agreement with other studies of similar nature [5,8,13].…”

“…In this study, we determined the differences in the characteristics of class I-IV risk factors and angiographic profile between younger and older patients with ACS. We selected an age cut-off of 40 y to define a premature CAD, based on previous Indian [1,11] and Indian subcontinent studies [2,[5][6][7].…”

“…The incidence of CAD is reported to be 12-16% among young Indian patients, with more than half of death related to cardiovascular disease occurring in patients below the age of 50 y and one-fourth of acute myocardial infarction cases being reported in patients under the age of 40 y [2]. Although numerous risk factors have been established to predict the development of ACS, these risk factor profile, severity of disease and its prognosis may be different between the young and older age groups [5]. Clinical studies have shown that as compared with older patients, patients with early-onset of cardiovascular disease may have preponderance of risk factors such as dyslipidaemia, positive family history, cigarette smoking, with lesser extent and less severe occurrence of CAD [2,6,7].…”

“…Further, it is reported that individuals from Indian subcontinent may develop coronary artery disease (CAD) at a higher rate and at an early age [4]. Onset of CAD before 40 y of age is considered as premature CAD [1,5].Although majority of studies reported that only about 3% of all CAD cases occur in <40 y of age, it should be considered as the 'tip of the iceberg' as young, asymptomatic patients usually do not undergo medical investigations. The incidence of CAD is reported to be 12-16% among young Indian patients, with more than half of death related to cardiovascular disease occurring in patients below the age of 50 y and one-fourth of acute myocardial infarction cases being reported in patients under the age of 40 y [2].…”

Atherosclerosis Is Associated with Neutrophil Lymphocyte Ratio As An Inflammatory Marker in Type 2 Diabetes Mellitus Patients with Coronary Artery Disease

“…In our study, the mean age of the patients in Group I (DM with CAD) was 54.73 (±8.94) years as compared to 56.59±13.63 years and 58.01±12.9 years, studies done by Assiri et al (2012) and Al-Saif et al (2011). It was 52.0±8.6 years in a study reported by Siddique et al (2010) and 56.6 years by Ullah M et al, (2011) in Bangladesh. 21,[23][24][25] Mean total count of WBC was found 9.90 ± (1.91) x 10 9 /L in Group I and 8.66 ± (1.37) x 10 9 /L in Group II.…”