Advances in the endoscopic diagnosis and treatment of Barrett’s neoplasia

Chedgy, Fergus; Kandiah, Kesavan; Thayalasekaran, Sreedhari; Subramaniam, Sharmila; Bhandari, Pradeep

doi:10.12688/f1000research.6996.1

Cited by 3 publications

(3 citation statements)

References 73 publications

(77 reference statements)

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“…Despite the fact that only 25 biopsies eventually were microscopically evaluated, 5 specimens exhibited metaplasia, raising more questions concerning the pathophysiology of FCG. In humans, esophageal metaplasia can progress to dysplasia and cancer (Barrett's esophagus) . According to their owners, no cat exhibited typical signs of esophageal disease or signs of esophageal disease were masked by FCG.…”

Section: Discussionmentioning

confidence: 99%

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Chronic Gingivostomatitis with Esophagitis in Cats

Kouki

Papadimitriou

Psalla

et al. 2017

Veterinary Internal Medicne

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BackgroundChronic gingivostomatitis in cats (FCG) is a debilitating disease with potentially deleterious effects on overall health.Hypothesis/ObjectivesLittle is known about the pathophysiology and overall impact of FCG. The aims of our study were to investigate whether gingivostomatitis occurs concurrently with esophagitis, if FCG treatment contributes to esophagitis and if esophagitis exacerbates signs of FCG.AnimalsFifty‐eight cats with clinical signs of FCG and 12 healthy control cats exhibiting no signs of oral disease, all client‐owned.MethodsProspective study. Physical, oral and endoscopic examinations were performed on all cats. Measurements of salivary and esophageal lumen pH were obtained from both groups. Biopsies were acquired from sites of esophageal inflammation in cats with FCG and from normal‐appearing esophageal mucosa in control cats.ResultsThe majority of cats with clinical signs of FCG exhibited some degree of esophagitis especially in the proximal (44/58) and distal (53/58) parts (P < 0.001) with or without columnar metaplasia, compared to controls. All cats lacked signs related to gastrointestinal disease. Salivary and esophageal lumen pH were not statistically different compared to controls.Conclusions and Clinical ImportanceFeline chronic gingivostomatitis seems to occur concurrently with esophagitis. Esophagitis also should be managed in cats with chronic gingivostomatitis because it may aggravate the existing condition.

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Section: Discussionmentioning

confidence: 99%

“…In humans, esophageal metaplasia can progress to dysplasia and cancer (Barrett's esophagus). 8 According to their owners, no cat exhibited typical signs of esophageal disease or signs of esophageal disease were masked by FCG.…”

Section: Discussionmentioning

confidence: 99%

Chronic Gingivostomatitis with Esophagitis in Cats

Kouki

Papadimitriou

Psalla

et al. 2017

Veterinary Internal Medicne

View full text Add to dashboard Cite

show abstract

“…I-scan, Fujinon intelligent chromoendoscopy, and autofluorescence imaging (AFI), are techniques that offer different filter options for the recognition and differentiation of mucosal abnormalities and vascular structures (14). I-scan, by manipulating the red, blue and green color of light, enhances vascular and mucosal structures.…”

Section: Diagnosis Of Bementioning

confidence: 99%