Complex early Barrett’s neoplasia at 3 Western centers: European Barrett’s Endoscopic Submucosal Dissection Trial (E-BEST)

Subramaniam, Sharmila; Chedgy, Fergus; Longcroft‐Wheaton, Gaius; Kandiah, Kesavan; Maselli, Roberta; Seewald, Stefan; Repici, Alessandro; Bhandari, Pradeep

doi:10.1016/j.gie.2017.01.027

Cited by 68 publications

(61 citation statements)

References 28 publications

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“…Recent studies have shown that Western endoscopists are able to perform the procedure despite the lack of opportunity to perform it in many patients with early gastric cancers. The findings in these studies, 22,23 although they were conducted in patients with Barrett's neoplasia, reverse the negative findings in many prior studies. Additionally, the accessories needed to perform ESD are now as available in the United States and Europe as they were in Japan.…”

Section: Red In Bluecontrasting

confidence: 45%

Endoscopic submucosal dissection for nonpolypoid colorectal dysplasia in patients with inflammatory bowel disease: in medias res

Soetikno

East

Suzuki

et al. 2018

Gastrointestinal Endoscopy

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Section: Red In Bluecontrasting

confidence: 45%

Endoscopic submucosal dissection for nonpolypoid colorectal dysplasia in patients with inflammatory bowel disease: in medias res

Soetikno

East

Suzuki

et al. 2018

Gastrointestinal Endoscopy

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“…Recent gastric ESD studies from Western centers have shown comparable outcomes to that of Eastern centers, particularly in critical endpoints such as R0 resection and complications (Table . In a prospective observational study of 191 EGC resected by ESD from a single Western referral center, en bloc and R0 resection rates of 98.4% and 90.2% for lesions meeting guideline criteria and 89.0% and 73.6% for lesions meeting expanded criteria, respectively, were achieved.…”

Section: Current Status Of Endoscopic Submucosal Dissection In Westermentioning

confidence: 96%

“…Western series of ESD for early Barrett's neoplasia have shown promising results, reporting en bloc and R0 resection rates of 90–100% and 79–81%, respectively (Table ). The overall rate of adverse events varies between 3% and 27% across different studies, less in centers with larger case load and more experienced endoscopists . One multicenter European study of 143 ESD for early Barrett's neoplasia identified 30 procedures as the threshold at which en bloc resection rates reach a plateau.…”

Section: Current Status Of Endoscopic Submucosal Dissection In Westermentioning

confidence: 99%

Endoscopic submucosal dissection in the West: Current status and future directions

Michael

Bourke

2017

Digestive Endoscopy

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Endoscopic submucosal dissection (ESD) was first conceptually described almost 30 years ago in Japan and is now widely practiced throughout East Asia. ESD expands the boundaries of endoscopic resection (ER) by allowing en bloc resection of large early neoplastic lesions within the gastrointestinal tract (GIT). This offers advantages over other ER techniques by facilitating definitive histological staging and curative treatment of early cancer in selected cases. Indeed, the experience of ESD in Eastern countries is significant, and excellent outcomes from high-volume centers are reported. The potential benefits of ESD are recognized by Western endoscopists, but its adoption has been limited. A number of factors contribute to this, including epidemiological differences in GIT neoplasia between Western and Eastern populations and limitations in training opportunities. In this review, we discuss the role of ESD, its current status and the future in Western endoscopic practice.

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“…is a well-established, minimally invasive treatment for superficial esophageal cancers (SEC). [1][2][3][4][5][6][7] However, esophageal ESD is a time-consuming procedure and requires more skill than gastric ESD because of the technical difficulties associated with the thin wall and narrow lumen of the esophagus. 2,[8][9][10][11] Pooling of liquid in the esophageal lumen sometimes bothers endoscopists because it is difficult to suction the liquid outside the transparent tip hood using an endoscope.…”

Section: Introduction E Ndoscopic Submucosal Dissection (Esd)mentioning

confidence: 99%

Continuous liquid‐suction catheter attachment for endoscope reduces volume of liquid reflux to the mouth in esophageal endoscopic submucosal dissection

Hatta

Koike

Okata

et al. 2019

Digestive Endoscopy

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Background and Aim Pooling of liquid in the esophageal lumen can worsen the field of vision and cause liquid reflux to the mouth, which leads to aspiration pneumonia, in esophageal endoscopic submucosal dissection (ESD). We developed a continuous liquid‐suction catheter attachment for the endoscope (CLCA) that has multiple tiny holes and can suction the liquid without causing mucosal injury. Thus, we aim to show the efficacy of CLCA in esophageal ESD. Methods This was a single‐blinded, randomized controlled trial involving patients with superficial esophageal cancer. The enrolled patients were randomly assigned to the conventional ESD (C‐ESD) or ESD with CLCA (CLCA‐ESD) groups. Primary endpoint was volume of liquid reflux to the mouth during the ESD procedure. Secondary endpoints were incidence of aspiration pneumonia and procedure time. Results Fifty patients were enrolled in this trial. Volume of liquid reflux to the mouth was significantly lower in the CLCA‐ESD group than in the C‐ESD group (mean: 10 vs 73 mL, P = 0.010). Furthermore, the incidence of aspiration pneumonia on computed tomography (CT) scan between the two groups was also significantly different (4.0% vs 32.0%, P = 0.023), although no significant difference was observed through chest radiography. In addition, procedure time tended to be shorter in the CLCA‐ESD group (P = 0.054). Conclusion This study first showed that use of CLCA in esophageal ESD reduced the volume of liquid reflux to the mouth and contributed to decreased incidence of aspiration pneumonia on CT scan (UMIN000018167).

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Complex early Barrett’s neoplasia at 3 Western centers: European Barrett’s Endoscopic Submucosal Dissection Trial (E-BEST)

Cited by 68 publications

References 28 publications

Endoscopic submucosal dissection for nonpolypoid colorectal dysplasia in patients with inflammatory bowel disease: in medias res

Endoscopic submucosal dissection for nonpolypoid colorectal dysplasia in patients with inflammatory bowel disease: in medias res

Endoscopic submucosal dissection in the West: Current status and future directions

Continuous liquid‐suction catheter attachment for endoscope reduces volume of liquid reflux to the mouth in esophageal endoscopic submucosal dissection

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