Adult neuroblastoma in the retroperitoneum

Wu, Xueliang; Dai, Yong‐Jun; Sun, Guangyuan; Wang, Likun; Liang, Han; Qu, Ming; Liu, Bo; Xue, Jun

doi:10.1097/md.0000000000013750

Cited by 6 publications

(5 citation statements)

References 12 publications

(10 reference statements)

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“…[2–4] There are only a few case reports about adulthood neuroblastoma. [5–7] While adult neuroblastoma that originated from thorax is exceedingly rare. Here we report a case of this kind with surgery treatment.…”

Section: Introductionmentioning

confidence: 99%

Primary thoracic neuroblastoma in an adult

Tan¹,

Li²,

et al. 2019

Medicine

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Rationale: Neuroblastoma is one of the most common malignant tumors in childhood, which mainly occurs in adrenal glands and peripheral sympathetic nerve system. Neuroblastoma occurring in adulthood is rare, and adults with neuroblastoma arising from thorax are exceedingly rare. A case of neuroblastoma that originated from thorax was reported, and was treated by resection operation. Patient concerns: A 46-year-old woman was admitted to our hospital with left side chest pain for 5 days. Laboratory examinations were all normal. Chest computerized tomogram (CT) showed a lesion with clear boundary that was located at the left dorsal pleura. The nature of the mass was heterogeneous, showing slight heterogeneous enhancement after contrast and there was no obvious necrosis. Diagnoses: Based on the morphologic and immunohistochemical features, the tumor diagnosis was favorable for neuroblastoma. Interventions: A resection operation was carried out. Outcomes: Three years postoperative, no sign of recurrence or metastasis has been observed. Lessons: Primary neuroblastoma in adulthood is rare and has poor prognosis. Resection can be an important treatment option, and combining with other methods like chemotherapy, stem cell transplantation, the survival rate may be improved.

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Section: Introductionmentioning

confidence: 99%

Primary thoracic neuroblastoma in an adult

Tan¹,

Li²,

et al. 2019

Medicine

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“…[ 8 , 12 – 16 ] The symptoms in most patients were relieved to varying degrees after chemotherapy. Radiotherapy has been also used for local disease control in pPNETs, [ 20 , 21 ] and it is applicable to patients who have not undergone complete RO. The patient herein had a poor postoperative condition and could not tolerate the side effects of chemotherapy.…”

Section: Discussionmentioning

confidence: 99%

Primary adult primitive neuroectodermal tumor of the bladder

Liu¹,

Zhang

2020

Medicine

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Rationale: A primary primitive neuroectodermal tumor (PNET) is a rare and highly malignant tumor that often occurs in the central nervous system of children and young adults. This tumor is rarely observed in the bladder. Patient concerns: In this paper, we describe the case of a 64-year-old man with a PNET of the bladder. He experienced dull pain in the lower left abdomen for 5 months (without any obvious inducement), which gradually became aggravated and intolerable. Diagnoses: Partial cystectomy was performed, and a PNET of the bladder, which is extremely rare, was confirmed. Interventions: Following cystectomy, the patient's general postoperative state was poor and he could not tolerate chemotherapy. Thus, he was subjected to pelvic radiotherapy for 2 weeks. Outcomes: His physical condition did not improve significantly after radiotherapy; however, we still plan to continue it. If the patient's physical condition improves, chemotherapy will be considered. Lessons: Most cases of PNETs are intravesical or at least mainly endophytic. However, in this case, the mucosal layer was barely involved, and the tumor mainly grew out of the bladder, which is very rare. The present case provides reference for the diagnosis of PNET.

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“…About 50% of the abdominal neuroblastoma is adrenal in origin [ 4 , 9 , 10 ]. Retroperitoneal neuroblastoma of size as big as 25 × 12 × 18 cm was reported in literature [ 11 ]. Our patient had stage 2B adrenal neuroblastoma based on the international neuroblastoma staging system (1990) [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Surgical Management of Giant L2 Adrenal Neuroblastoma in Adult Male

Thapa

Yadav

Pant³

et al. 2020

Case Reports in Urology

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Neuroblastoma is an embryonal malignancy that arises from neural crest cells. Adult adrenal neuroblastoma is a rare disease, and less than 100 cases were reported in the literature. Adult neuroblastoma commonly presents with abdominal (retroperitoneal) lump and pain. A 35-year-old male patient presented with a giant ( 20 cm × 17 cm × 12 cm ) nonfunctional left adrenal mass. He underwent en-bloc surgical excision of the left adrenal gland along with the left kidney. Histopathological examination revealed adrenal neuroblastoma (stage 2B, L2). We present here the surgical management of the rare adult adrenal neuroblastoma.

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Adult neuroblastoma in the retroperitoneum

Cited by 6 publications

References 12 publications

Primary thoracic neuroblastoma in an adult

Primary thoracic neuroblastoma in an adult

Primary adult primitive neuroectodermal tumor of the bladder

Surgical Management of Giant L2 Adrenal Neuroblastoma in Adult Male

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