Adhesion to the yeast cell surface as a mechanism for trapping pathogenic bacteria by Saccharomyces probiotics

Tiago, Fabiana da Conceição Pereira; Martins, Flaviano S.; Souza, Éricka Lorenna de Sales e; Pimenta, Paulo Filemon Paolucci; Araújo, Helena Rocha Corrêa de; Castro, Ieso de Miranda; Brandão, Rogélio Lopes; Nicoli, Jacques R.

doi:10.1099/jmm.0.042283-0

Cited by 111 publications

(95 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In an investigation probiotic yeast S.cerevisiae var boulardii caused a statistically significant reduction in the number of cells of Listeria monocytogenes, Pseudomonas aerugenosa and Staphylococcus aureus and a decrease in the growth rate of Listeria monocytogenes and Pseudomonas aerugenosa [50]. Yeasts act against enteric pathogens by many different mechanisms, such as prevention of bacterial adherence and translocation in the intestinal epithelial cells, production of factors that neutralize bacterial toxins and modulation of the host signaling pathway with proinflammatory response during bacterial infection [8,51,52]. …”

Section: Discussionmentioning

confidence: 99%

Probiotic Potential of Yeasts Isolated From Traditional Indian Fermented Foods

Syal¹,

Vohra²

2013

Int J of Micr Res

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Probiotic Potential of Yeasts Isolated From Traditional Indian Fermented Foods

Syal¹,

Vohra²

2013

Int J of Micr Res

View full text Add to dashboard Cite

“…Not surprisingly, and since S. boulardii has been the most widely probiotic yeast studied, its mechanisms of action against enteropathogens and disorders of the GIT are the most well described among all S. cerevisiae probiotic strains (Czerucka et al 2007;Tiago et al 2012). It has been demonstrated that S. boulardii binds and neutralizes pathogenic enteric bacteria (C. difficile, Escherichia coli, Vibrio cholera, Salmonella, and Shigella spp.)…”

Section: Mechanisms Of Action Of Probiotic S Cerevisiae Strainsmentioning

confidence: 98%

Probiotic Saccharomyces cerevisiae strains as biotherapeutic tools: is there room for improvement?

Palma

Zamith-Miranda

Martins

et al. 2015

Appl Microbiol Biotechnol

View full text Add to dashboard Cite

The probiotic yeast Saccharomyces cerevisiae var boulardii is widely used as a low cost and efficient adjuvant against gastrointestinal tract disorders such as inflammatory bowel disease and treatment of several types of diarrhea, both in humans and animals. S. boulardii exerts its protective mechanisms by binding and neutralizing enteric pathogens or their toxins, by reducing inflammation and by inducing the secretion of sIgA. Although several S. cerevisiae strains have proven probiotic potential in both humans and animals, only S. boulardii is currently licensed for use in humans. Recently, some researchers started using S. boulardii as heterologous protein expression systems. Combined with their probiotic activity, the use of these strains as prophylactic and therapeutic proteins carriers might result in a positive combined effort to fight specific diseases. Here, we provide an overview of the current use of S. cerevisiae strains as probiotics and their mechanisms of action. We also discuss their potential to produce molecules with biotherapeutic application and the advantages and hurdles of this approach. Finally, we suggest future directions and alternatives for which the combined effort of specific immunomodulatory effects of probiotic S. cerevisiae strains and ability to express desired foreign genes would find a practical application.

show abstract

“…For L. reuteri, instead, a strong antibacterial potential was observed against E. coli by means of organic acids, ethanol, and reuterin production [36]. Concerning S. boulardii, the antimicrobial capacity has been studied in terms of adhesion of pathogenic bacteria to its surface as a mechanism for trapping [37].…”

Section: Discussionmentioning

confidence: 99%

Antibiofilm and Antiadhesive Activities of Different Synbiotics

Stefania¹,

Mir²,

Diana³

et al. 2017

J Prob Health

View full text Add to dashboard Cite

Synbiotics are a combination of probiotic bacteria and the growth promoting prebiotic ingredients that purport "synergism".Probiotics are well known for their ability to restore a healthful balance of commensal microbes supporting the repair of hyper-permeable epithelial barriers and interfering with infection. The present research was designed to evaluate the anti-virulence role of cell-free supernatants of synbiotic cultures.The effect of prebiotics fructo-oligosaccharide, inulin and isomaltose on probiotic Lactobacillus acidophilus, Lactococcus lactis, Lactobacillus casei, Lactobacillus reuteri and Saccharomyces boulardii growth, fermentation products has been investigated. Cell-free supernatants of synbiotics cultures have been studied for their antimicrobial, antibiofilm and anti-adhesion properties. Results highlight that prebiotics can enhance the antimicrobial and anti-virulence activities of probiotics against potential pathogens Staphylococcus aureus and Escherichia coli.The present research supports, for the first time, the value of anti-virulence activity of metabolites produced by synbiotics suggesting their use as a suitable adjuvant in antibacterial treatment.

show abstract

Adhesion to the yeast cell surface as a mechanism for trapping pathogenic bacteria by Saccharomyces probiotics

Cited by 111 publications

References 33 publications

Probiotic Potential of Yeasts Isolated From Traditional Indian Fermented Foods

Probiotic Potential of Yeasts Isolated From Traditional Indian Fermented Foods

Probiotic Saccharomyces cerevisiae strains as biotherapeutic tools: is there room for improvement?

Antibiofilm and Antiadhesive Activities of Different Synbiotics

Contact Info

Product

Resources

About