Adesão farmacológica e conhecimento de pacientes anticoagulados

Figueirêdo, Thaisa Remigio; Costa, Christefany Régia Braz; Silveira, Maria Mariana Barros Melo da; Araújo, Hirla Vanessa Soares de; Silva, Tamara; Bezerra, Simone Maria Muniz da Silva

doi:10.15446/av.enferm.v36n2.62641

Cited by 3 publications

(2 citation statements)

References 11 publications

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“…(9) Destacam-se como desafio para eficácia terapêutica dos ACO a monitorização efetiva e a adesão do paciente ao tratamento, além disso, o domínio do conhecimento dos profissionais de saúde sobre o anticoagulante oral, assim como a transmissão desse conhecimento, também é um fator que repercute na qualidade do tratamento. (10,11) Estudos indicam uma carência de informações prestadas pela equipe de saúde aos pacientes em uso de anticoagulantes, sendo o conhecimento desses indivíduos um fator de suma importância na segurança da terapia, podendo proporcionar melhor adesão no uso dos ACO, melhor controle dos níveis de coagulação e redução de complicações. (11,12) Portanto diante do exposto e da necessidade observada na prática clínica, este estudo tem como objetivo avaliar o conhecimento sobre a terapêutica medicamentosa de indivíduos em uso de anticoagulantes orais.…”

Section: Introductionunclassified

Avaliação Do Conhecimento Sobre a Terapêutica Medicamentosa De Indivíduos Em Uso De Anticoagulantes Orais

Silva¹,

Silveira²,

Silva³

et al. 2022

Enfermagem Em Foco

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Objetivo: Avaliar o conhecimento sobre a terapêutica medicamentosa de indivíduos em uso de anticoagulantes orais. Métodos: Estudo transversal, quantitativo, com participação de 90 indivíduos em uso de anticoagulantes orais acompanhados em ambulatório de anticoagulação em Recife-PE. Os dados foram coletados de abril a julho de 2020 através de dois questionários, analisados por estatística descritiva e dispostos em tabelas. Resultados: A maioria dos indivíduos (42,2%) apresentou conhecimento adequado acerca do tratamento. Na associação do conhecimento com outras variáveis, houve significância estatística entre conhecimento adequado com resultados do International Normalized Ratio dentro da faixa indicada (p=0,001) e com idade menor que 60 anos (p=0,018), e entre conhecimento inadequado com baixa escolaridade (p=0,045), hipertensão (p=0,009) e tabagismo (p=0,041). Conclusão: A maioria dos indivíduos apresentou conhecimento adequado acerca do tratamento. Houve associação significativa entre conhecimento adequado e resultados do INR e entre a idade, assim como conhecimento inadequado e baixa escolaridade, não ser tabagista e hipertensão.

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Section: Introductionunclassified

Avaliação Do Conhecimento Sobre a Terapêutica Medicamentosa De Indivíduos Em Uso De Anticoagulantes Orais

Silva¹,

Silveira²,

Silva³

et al. 2022

Enfermagem Em Foco

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“…32 The investigation of factors associated with nonadherence to the use of OACs may be helpful to expanding knowledge on its occurrence in clinical practice and substantiate interventions to help patients achieve treatment goals. [33][34][35] Some factors reported to interfere with adherence are sociodemographic and clinical variables, cognition status, emotional and psychological aspects, occupation 36,37 and the complexity of drug therapy. 38 In the scenario of thromboembolism, improving patients´knowledge on their health condition and associated risk factors contribute to reduce mortality.…”

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Factors associated with nonadherence to the use of coumarin derivatives or direct oral anticoagulants: A systematic review of observational studies

Sousa

Guimarães

Viana

et al. 2022

Brit J Clinical Pharma

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Nonadherence to thromboprophylaxis treatment with oral anticoagulants (OAC) is a public health problem and may be associated with high mortality rates. We sought to synthesize the factors associated with nonadherence to therapy with coumarin derivatives or direct oral anticoagulants. A systematic review was performed at electronic databases Medline, Embase, CINAHL, Lilacs and grey literature (Google Scholar, MedNar, OpenGray, ProQuest Dissertations and Theses, and hand search).This study was conducted according to Cochrane's method and PRISMA. The registration on PROSPERO is CRD42020223555. Overall, 1270 studies were identified and nine studies were selected for this review. In hand searching, 77 studies were found, but none included. The associated factors with nonadherence were heterogeneous, and some factors were described as both risk and protection for nonadherence, with few variables showing consistent results among the studies. Variables reported only as risk factors were "male sex", "hospitalization", "Charlson score" and "bleeding", while "white race", CHA 2 DS 2 VASc (score range 2-9)" and "polypharmacy" were reported only as protective factors. Most studies did not present details in the description of concepts and methods to assess nonadherence. In clinical practice, the knowledge on factors associated with nonadherence is helpful to identifying patients at higher risk of complications that would benefit from individualized interventions.

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Accuracy of an adherence score and time in therapeutic range among patients on chronic use of vitamin K antagonists

Simonetti

Oliveira

Lourenço

et al. 2021

RSD

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To validate and analyze the accuracy of the Simonetti adherence score among patients on chronic use of vitamin K antagonists and their time in therapeutic range (TTR) of the international normalized ratio as a measure of quality of anticoagulation. A prospective cohort study with a nonrandomized intervention in patients from an anticoagulation center of a public hospital. Baseline data were collected from May to September 2017, and follow-up data were obtained eight months after a nurse-led educational intervention, which was given to all patients after consent form and after applying the adherence score (N=205). The intervention was undertaken through 30-40 min conversation about relevant factors that had been previously identified in the score derivation study, which comprised drug-drug interactions, inadequate OAC use, comorbidities, effects of food on vitamin K absorption, and invasive procedures. A receiver operating characteristic (ROC) curve was applied to validate the adherence score in terms of prediction of INR out of recommended therapeutic range. At baseline, mean adherence score was 44.69 and standard deviation (SD) was 18.37, and mean TTR was 41.07 (SD 15.40). Patients were reassessed after 8 months. At follow-up, there were significant improvements in mean adherence score 54.28 (SD 13.13), and in mean TTR 50.99 (SD 26.10). The Simonetti adherence score yielded high performance and accuracy in clinical practice among patients on chronic use of vitamin K antagonists. Our data indicate that nurse led educational intervention yielded favorable impact in terms of adherence score and TTR improvements.

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Adesão farmacológica e conhecimento de pacientes anticoagulados

Cited by 3 publications

References 11 publications

Avaliação Do Conhecimento Sobre a Terapêutica Medicamentosa De Indivíduos Em Uso De Anticoagulantes Orais

Avaliação Do Conhecimento Sobre a Terapêutica Medicamentosa De Indivíduos Em Uso De Anticoagulantes Orais

Factors associated with nonadherence to the use of coumarin derivatives or direct oral anticoagulants: A systematic review of observational studies

Accuracy of an adherence score and time in therapeutic range among patients on chronic use of vitamin K antagonists

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