Acute transient spinal paralysis and cardiac symptoms following an accidental epidural potassium infusion – a case report

Abstract

BackgroundTo describe a case of an accidental epidural potassium infusion leading to an acute transient spinal paralysis and cardiac symptoms and review the literature on that topic.Case presentationWe report the case of an accidental infusion of 900 mg potassium chloride 7.45% (KCl) into the epidural space, which occurred during epidural analgesia in a 74-year-old patient suffering from immobilization due to lumbar back pain as well as from a paralytic Ileus. The event was resulting in vegetative symptoms, such as tachycardia and hypertension accompanied by a motor complete tetraplegia (AIS B) sub C2 with respiratory depression. The endotracheal intubation was necessary.The patient was treated with 40 mg dexamethasone intravenously, as well an epidural lavage with sodium chloride solution 0.9% (NaCl) through the epidural catheter. The neurologic symptoms completely resolved within five days. An elevation of troponin-T values and a reduced left ventricular ejection fraction (LVEF) of 40% accompanied by transient pectanginous pain were documented. An exertional dyspnea remained.ConclusionsA symptom complex with elevated sympathetic nervous system activity up to a stress cardiomyopathy is possible following epidural potassium infusion. Additionally, generalized pain and muscle spasticity evolve and a progressive acute spinal cord injury syndrome can occur within minutes, accompanied by respiratory depression. Treatment consists of early intensive care and the symptomatic therapy of the associated symptoms, leading in most of the reported cases to a good clinical outcome.

Accidental administration of tranexamic acid into the epidural space: a case report

“…Four individual case reports used single-dose bolus volumes of 10 mL, 11 20 mL, 12 40 mL, 13 and 50 mL, 14 respectively, with no comment on the time periods over which the boluses were given. Three different reports used higher rates of saline infusion, each for six hours: one case with 100 mLÁhr -1 15 and two cases with 99 mLÁhr -1 .…”