Acute tensile strength analysis of collagen solder for mesh fixation to the peritoneal surface

Abstract

These values are similar to the 200-500 g/cm2 acute strengths reported for sutured or stapled peritoneal closure. Mesh fixation by solder is feasible, and further development of this technology is warranted.

Histologic assessment of mesh fixation following laser-assisted tissue soldering in a lapine model

“…Acute solder bond strengths were similar in all groups (range 261.5 AE 170.3 to 465.3 AE 288.2 g/cm 2 ) and were not statistically different from stapled controls (215.8 AE 117.8 g/cm 2 ). These values are similar to 200-500 g/cm 2 acute strengths reported for sutured or stapled peritoneal closure in experimental models [38].…”

“…This preliminary study demonstrates that laser-assisted tissue soldering is feasible and is capable of achieving intraperitoneal mesh fixation without the use of staples or permanent means of mesh fixation to tissue. Previous work from our laboratory demonstrates that temperature controlled laser collagen soldering results in satisfactory acute tensile strengths after mesh fixation and demonstrates that adhesion formation is reduced in scenarios that cover the mesh material with the collagen solder [38,39]. Tensile strength measurements were conducted immediately following mesh fixation using the techniques and parameters of the current study.…”

Techniques of mesh fixation in laparoscopic ventral hernia repair: the surgical enigma - a review

“…21,22 An experiment of laser assisted tissue welding for solder fixation of mesh to peritoneum has also been successful with no statistical difference noted between stapled and soldered mesh in animal model. 23 In addition to all of these, a concept of selfadhering meshes also came in to the picture but in respect of LVHR, it is still at an experimental stage. 24 In practice, commonly used fixation devices are nonabsorbable tacks, absorbable tacks, sutures and another technique currently evolving is fibrin/tissue glue.…”

Preliminary Assessment of Photoactivated Antimicrobial Collagen on Bioburden in a Murine Pressure Ulcer Model

“…[15][16][17][18] Previous work with derivatized collagen solder formulations demonstrated that high concentration preparations could be cast into films for subsequent sectioning into strips for application to the weld site. [19][20][21][22][23] Collagen is biocompatible and bioabsorbable, and can be used as a carrier for biologically relevant molecules and chromophores.…”