Acute Responses of Cardiac Biomarkers to Intermittent and Continuous Exercise Are Related to Age Difference but Not I/D Polymorphism in the ACE Gene

Falahati, Akram; Arazi, Hamid; Suzuki, Katsuhiko

doi:10.3389/fphys.2020.00665

Cited by 2 publications

(1 citation statement)

References 48 publications

(58 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The improved cardiovascular [ 72 ] and metabolic [ 73 ] consequences induced by HIIT are the reason for this hypothesis. In addition, HIIT is also safe for many high-risk populations [ 72 ], even at an advanced age [ 74 ], including patients with CKD [ 18 ], which makes HIIT an attractive therapeutic strategy in CKD patients. However, there is a lack of human studies, and most of the research studies have been conducted on animal models; as animal research may be a poor predictor of human experience, these papers were not included in this study.…”

Section: Resultsmentioning

confidence: 99%

Effects of Different Types of Exercise on Kidney Diseases

Arazi

Mohabbat

Saidie

et al. 2022

Sports

Self Cite

View full text Add to dashboard Cite

The effects of exercise on kidney function have been studied for more than three decades. One of the most common health issues among patients with chronic kidney disease (CKD) is a lack of physical activity, which leads to a low exercise capacity in these patients. The majority of maintenance hemodialysis (MHD) patients do not exercise at all. At each stage of dialysis, patients lose 10–12 g of their amino acids through blood sampling. Dialysis also leads to increased cortisol and circadian rhythm sleep disorders in hemodialysis (HD) patients. Studies have also reported higher C-reactive protein levels in HD patients, which causes arterial stiffness. Exercise has a variety of health benefits in these patients, including improved blood pressure control, better sleep, higher physical function, and reduced anxiety and depression. On the other hand, it should be noted that intense exercise has the potential to progress KD, especially when conducted in hot weather with dehydration. This review aimed to investigate the effects of different types of exercise on kidney disease and provide exercise guidelines. In conclusion, moderate-intensity and long-term exercise (for at least a 6-month period), with consideration of the principles of exercise (individualization, intensity, time, etc.), can be used as an adjunctive treatment strategy in patients undergoing dialysis or kidney transplantation.

show abstract

Section: Resultsmentioning

confidence: 99%

Effects of Different Types of Exercise on Kidney Diseases

Arazi

Mohabbat

Saidie

et al. 2022

Sports

Self Cite

View full text Add to dashboard Cite

show abstract

Cardiac biomarker responses following high-intensity interval and continuous exercise: the influence of ACE-I/D gene polymorphism and training status in men

Falahati,

Arazi

2024

Physiological Genomics

View full text Add to dashboard Cite

This study aimed to investigate the relationship between pre and post-exercise cardiac biomarker release according to athletic status (trained vs. untrained); and to establish whether the I/D polymorphism in the ACE gene had an influence on cardiac biomarkers release with specific regard on the influence of the training state. We determined cTnI and NT-proBNP in 29 trained and 27 untrained male soccer players before and after moderate-intensity continuous exercise (MICE) and high-intensity interval exercise (HIIE) running tests. Trained soccer players had higher pre (trained: 0.014±0.007 ng/mL; untrained: 0.010±0.005 ng/mL) and post HIIE (trained: 0.031±0.008 ng/mL; untrained: 0.0179±0.007) and MICE (trained: 0.030±0.007 ng/mL; untrained: 0.018±0.007) cTnI values than untrained subjects, but the change with exercise (ΔcTnI) was similar between groups. There was no significant difference in baseline and post-exercise NT-proBNP between groups. NT-proBNP levels were elevated after both HIIE and MICE. Considering three ACE genotypes, the mean pre-exercise cTnI values of trained group (DD: 0.015±0.008 ng/mL; ID: 0.015±0.007 ng/mL; II: 0.014±0.008 ng/mL) and their untrained counterparts (DD: 0.010±0.004 ng/mL; ID: 0.011±0.004 ng/mL; II: 0.010±0.006 ng/mL) did not show any significant difference. To sum up, noticeable difference in baseline cTnI was observed which was related to athletic status, but not ACE genotypes. Neither athletic status nor ACE genotypes seem to affect the changes in cardiac biomarkers in response to HIIE and MICE, indicating that the ACE gene does not play a significant role in the release of exercise-induced cardiac biomarkers indicative of cardiac damage in Iranian soccer players.

show abstract

Acute Responses of Cardiac Biomarkers to Intermittent and Continuous Exercise Are Related to Age Difference but Not I/D Polymorphism in the ACE Gene

Cited by 2 publications

References 48 publications

Effects of Different Types of Exercise on Kidney Diseases

Effects of Different Types of Exercise on Kidney Diseases

Cardiac biomarker responses following high-intensity interval and continuous exercise: the influence of ACE-I/D gene polymorphism and training status in men

Contact Info

Product

Resources

About