Acute Pancreatitis Following Gastrointestinal Endoscopy without Ampullary Cannulation

Post-procedure Elevated Amylase and Lipase Levels After Double-Balloon Enteroscopy: Relations with the Double-Balloon Technique

“…The causal mechanism of acute pancreatitis is uncertain, but might potentially involve local trauma to the pancreas during the procedure or the release of as yet undefined inflammatory mediators that are secreted in response to the mechanical stress. There are rare published cases with acute pancreatitis even after upper and lower gastrointestinal endoscopy, and the authors suggested that mechanical stress might have caused acute pancreatitis [16][17][18][19]. In accordance with these reports, in our study, the findings suggest that the pancreas might be subject to severe mechanical stress by the enteroscope itself and by the inflated overtube balloon, particularly during the first advancement of the instrument.…”

The effects of different mechanisms on the development of post-ERCP pancreatitis in an ERCP model in rats

“…Both sphincter of Oddi spasm and/or edematous hemorrhagic papilla induced by endoscopically direct trauma lead to pancreatic edema and pancreatitis by reducing the flow rate of pancreatic fluid (14)(15)(16). Based on this theory, treatments aiming at decreasing the pressure in sphincter of Oddi have been started for reducing the post-ERCP pancreatitis risk.…”

Acute pancreatitis following oesophagogastroduodenoscopy.

“…Deschamps et al described a case of acute pancreatitis occurring after upper endoscopy for evaluation of anaemia in a 58-year-old woman with Grave’s disease 19. A hiatal hernia without evidence of esophagitis was identified during the procedure, and an easily accessed duodenum was without any lesions.…”

“…Compared with the other reported cases, the case presented above was particularly severe (manifested by SIRS, pleural effusion, marked ascites and more extensive pancreatic involvement) and hospital course was protracted. The other case that appeared to be very severe and eventually required a laparotomy,19 one can argue that a more conservative approach may have been successful if more advanced imaging modalities that could have ruled out urgent or emergent complications were used. The reason for the level severity noted in this case remains unclear, even though the role of partial liver donation was considered.…”