Acute non-cardiogenic lung injury in benign tertian malaria

Acute Respiratory Distress Syndrome due to Vivax Malaria

“…We reviewed 11 cases of vivax malaria with severe pulmonary involvement [6][7][8][9][10]. There are several clinical manifestations of malaria, and clinical evolution depends on factors of the parasite, the host, and on geographic characteristics [10] severe malaria caused by P falciparum includes severe anaemia, jaundice, renal failure, cerebral malaria, and ARDS.…”

“…There are several clinical manifestations of malaria, and clinical evolution depends on factors of the parasite, the host, and on geographic characteristics [10] severe malaria caused by P falciparum includes severe anaemia, jaundice, renal failure, cerebral malaria, and ARDS. Sporadically, all of these complications have been reported in vivax malaria [6][7][8][9][10].…”

“…The level of parasitemia is variable in cases of severe pulmonary involvement. Two patients presented parasitemia counts higher than 2% [8,10], and another case was defined as "heavy" [7]. On the other hand, four patients had levels of parasitemia that were considered low; three had < 2% [13,15], and one case had 1,784 trophozoites/mm 3 [10].…”

Pulmonary toxicity with mefloquine

“…Furthermore, the histological picture showed neither neutrophilic infiltrates or viral inclusions. Acute lung injury can occur secondary to malaria, but typically, only in the more severe forms of the disease, reflected by high acute physiological scores [4][5][6][7]. The patient had only a low parasitaemia, which disappeared on the second day of hospital admission.…”

“…BAL fluid showed an increased number of cells (82610 6 ?L -1 ), with 43% neutrophils, 38.5% alveolar macrophages, 14.5% lymphocytes, 1.5% nonsegmented neutrophils, 1% eosinophils, and 1% basophils. Trimethoprim-sulfamethoxazole was started empirically after bronchoscopy, but was stopped after 48 h because P. carinii were absent in the BAL and the Western blot for HIV was negative.…”