Acute Respiratory Distress Syndrome due to Vivax Malaria

Mukherjee, Tapajyoti; Lavania, AK

doi:10.1016/s0377-1237(08)80026-3

Cited by 3 publications

(3 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…16 Researchers suggest that an accumulation of pulmonary monocytes occurs leading to an intravascular inflammatory response, which contributes to pulmonary manifestations in malaria. 17 Severe pulmonary complications of vivax malaria usually appear from six hours to eight days after the initiation of anti-malarial treatment. In some cases, worsening of the clinical picture was seen after reduction of parasite counts, reinforcing the possibility of an immune mediated inflammatory response.…”

Section: Discussionmentioning

confidence: 99%

“…In some cases, worsening of the clinical picture was seen after reduction of parasite counts, reinforcing the possibility of an immune mediated inflammatory response. 14,15,17 In most reported cases of ARDS due to vivax malaria, diagnosis was made by PBF examination without molecular diagnostic confirmation, thus co-infection with P. falciparum could not be ruled out, and most of the reported cases were treated for both P. falciparum and P. vivax. 18 Anstey et al raised the hypothesis that the widespread use of chloroquine and doxycycline in malaria-endemic areas could be attenuating or diminishing the number of severe cases of vivax malaria because of the anti-inflammatory properties of these drugs.…”

Section: Discussionmentioning

confidence: 99%

“…16 The possible role of an inflammatory mechanism in pulmonary damage by vivax malaria suggests a potential benefit with the use of corticosteroid therapy. 17 However, there is no evidence that supports this therapeutic approach.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Acute respiratory distress syndrome in a case of Plasmodium vivax malaria

Malik

Ponvijaya

Sajjan

et al. 2021

Int J Community Med Public Health

View full text Add to dashboard Cite

Acute respiratory distress syndrome (ARDS) is a life threatening complication of many infectious diseases like malaria, H1N1, bacterial pneumonia, and leptospira. Malaria is an important treatable cause of ARDS. ARDS can develop either at initial presentation or after initiation of treatment when the parasitaemia is falling and patient is improving. 58 year old female presented with high grade fever and breathlessness since 5 days. Arterial blood gas (ABG) on admission showed type 1 respiratory failure and chest X-ray was suggestive of ARDS. Thus patient was shifted to intensive care unit and was put on non-invasive ventilation. PBS was positive for Plasmodium vivax malaria and patient was started on antimalarial drugs. Considering the epidemic of H1N1 swab was sent for polymerase chain reaction (PCR) which turned out to be negative. Thus antimalarial and supportive treatment for ARDS was continued. Patient was discharged on day 11 and started on tablet primaquine to prevent relapse. ARDS is a hard to predict late complication of severe malaria. ARDS in malaria is a disease with high mortality. Early diagnosis and institution of specific antimalarial treatment along with assisted ventilation can be life-saving.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Acute respiratory distress syndrome in a case of Plasmodium vivax malaria

Malik

Ponvijaya

Sajjan

et al. 2021

Int J Community Med Public Health

View full text Add to dashboard Cite

show abstract

Respiratory Complications of Plasmodium vivax Malaria: Systematic Review and Meta-Analysis

Val

Machado

Barbosa

et al. 2017

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Malaria, a major global public health problem, is mainly caused by and, and is responsible for nearly half a million deaths annually. Although malaria was not believed to cause severe disease, recent robust studies have proved otherwise. However, the clinical spectrum and pathogenesis of severe vivax malaria and, especially, its respiratory complications remain poorly understood. A systematic search for articles reporting respiratory complications associated with vivax malaria was performed in Lilacs, Cochrane, Scielo, Web of Science, and Medline databases irrespective of publication date. Prevalence of acute respiratory distress syndromeARDS) and associated mortality among vivax patients were calculated from cross-sectional and longitudinal studies, whereas factors associated with mortality were calculated from data pooled from case reports and series of cases. A total of 101 studies were included (49 cross-sectional or longitudinal and 52 case reports or series of cases). Prevalence of ARDS was 2.8% and 2.2% in children and adults, respectively, with nearly 50% mortality. Moreover, female sex ( = 0.013), having any comorbidity ( = 0.036), lower body temperature ( = 0.032), lower hemoglobin ( = 0.043), and oxygen saturation ( = 0.053) values were significantly associated with mortality. malaria respiratory complications included ARDS and were associated with high mortality. Demographics and clinical characteristics upon presentation to hospital were associated with mortality among patients with respiratory complications in vivax malaria. This study reaffirms the evidence of severe and fatal complications of malaria and its associated respiratory complications.

show abstract

Plasmodium vivax Induced Acute Respiratory Distress Syndrome – A Diagnostic and Therapeutic Dilemma in Preeclampsia

Sharma

Suneja

Yadav

et al. 2017

JCDR

View full text Add to dashboard Cite

A 27-year-old woman, G2P1L1 at 36 weeks gestation presented to our hospital with complaints of fever with chills and rigor since five days. There was no prior history of any obstetric or medical problems. She underwent lower segment caesarean section four years back for breech presentation.On examination, she was conscious and oriented, having mild pallor and icterus. Her temperature was 102.6°F, PR 128 bpm, RR 18/ min, BP 146/94 mmHg, O 2 saturation 100% at room air. Chest was clear with normal vesicular breathing and cardiovascular system. There was no hepatosplenomegaly and fundal height was 36 weeks, cephalic relaxed and fetal heart rate was 140 bpm regular. Laboratory investigation were -Hb 10.2 g%, TLC 8400, platelet count 1.2 L, random blood sugar was 84 mg/dl, serum electrolytes Na + 136 and K + 3.8 mg, total serum bilirubin was 2.82, indirect 2.14 and direct 0.68, SGOT/PT 69/60, blood urea 18 mg/dl and serum creatinine 0.7 mg/dl. Dipstick showed 1+ albuminuria. Viral markers, peripheral smear for malarial parasite and dengue serology were negative. Although widal was positive in titres of 1:160, urine and blood culture reported no growth. Ultrasound whole abdomen revealed mild splenomegaly. Provisional diagnosis of non severe preeclampsia with typhoid fever was made.

show abstract

Acute Respiratory Distress Syndrome due to Vivax Malaria

Cited by 3 publications

References 8 publications

Acute respiratory distress syndrome in a case of Plasmodium vivax malaria

Acute respiratory distress syndrome in a case of Plasmodium vivax malaria

Respiratory Complications of Plasmodium vivax Malaria: Systematic Review and Meta-Analysis

Plasmodium vivax Induced Acute Respiratory Distress Syndrome – A Diagnostic and Therapeutic Dilemma in Preeclampsia

Contact Info

Product

Resources

About