Acute Limb Ischemia and Coronary Artery Disease in a Case of Kimura’s Disease

Heo, Woon; Jun, Hee Jae; Kang, Do Kyun; Min, Ho-Ki; Hwang, Youn‐Ho; Kim, Ji Yong; Nam, Kyung Han

doi:10.5090/kjtcs.2017.50.2.114

Cited by 12 publications

(2 citation statements)

References 6 publications

(7 reference statements)

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“…Based on recent studies, peripheral arterial disorder is the main factor in the progression of hind limb ischemia (HLI). Chronic and acute arterial occlusions are caused primarily by occlusive arterial diseases and could block the blood perfusion into the limbs, as well as related tissues and organs ( Heo et al, 2017 ). During the ischemia pathogenesis, decreasing the hypoxic cell’s metabolism, increasing the level of intracellular free radicals, and forming a stressful inflammatory network in the ischemic tissue microenvironment can negatively disturb the cellular population’s viability and function ( Khodayari et al, 2019 ).…”

Section: Limb Ischemia Pathogenesis: Pathways and Mechanismsmentioning

confidence: 99%

Stem Cell Therapy in Limb Ischemia: State-of-Art, Perspective, and Possible Impacts of Endometrial-Derived Stem Cells

Khodayari

Ebrahimi‐Barough

et al. 2022

Front. Cell Dev. Biol.

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As an evidence-based performance, the rising incidence of various ischemic disorders has been observed across many nations. As a result, there is a growing need for the development of more effective regenerative approaches that could serve as main therapeutic strategies for the treatment of these diseases. From a cellular perspective, promoted complex inflammatory mechanisms, after inhibition of organ blood flow, can lead to cell death in all tissue types. In this case, using the stem cell technology provides a safe and regenerative approach for ischemic tissue revascularization and functional cell formation. Limb ischemia (LI) is one of the most frequent ischemic disease types and has been shown to have a promising regenerative response through stem cell therapy based on several clinical trials. Bone marrow-derived mononuclear cells (BM-MNCs), peripheral blood CD34-positive mononuclear cells (CD34+ PB-MNCs), mesenchymal stem cells (MSCs), and endothelial stem/progenitor cells (ESPCs) are the main, well-examined stem cell types in these studies. Additionally, our investigations reveal that endometrial tissue can be considered a suitable candidate for isolating new safe, effective, and feasible multipotent stem cells for limb regeneration. In addition to other teams’ results, our in-depth studies on endometrial-derived stem cells (EnSCs) have shown that these cells have translational potential for limb ischemia treatment. The EnSCs are able to generate diverse types of cells which are essential for limb reconstruction, including endothelial cells, smooth muscle cells, muscle cells, and even peripheral nervous system populations. Hence, the main object of this review is to present stem cell technology and evaluate its method of regeneration in ischemic limb tissue.

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Section: Limb Ischemia Pathogenesis: Pathways and Mechanismsmentioning

confidence: 99%

Stem Cell Therapy in Limb Ischemia: State-of-Art, Perspective, and Possible Impacts of Endometrial-Derived Stem Cells

Khodayari

Ebrahimi‐Barough

et al. 2022

Front. Cell Dev. Biol.

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“…It had been reported that eosinophils contain various amounts of tissue factor (TF) and some researchers had concluded that relatively high TF in patients with hypereosinophilia might lead to an increased thrombotic risk [ 8 ]. A patient with KD was reported to be complicated with acute limb ischemia and coronary artery disease [ 9 ]. The D-dimer in the patient we reported was at a high level.…”

Section: Discussionmentioning

confidence: 99%

Kimura disease with Allergic Bronchopulmonary Aspergillosis: a case report

Fan

Chen

et al. 2022

Allergy Asthma Clin Immunol

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Background Kimura disease (KD) is a rare chronic idiopathic condition of unknown etiology that is prevalent in Asian males. It often causes subcutaneous lumps and enlarged lymph nodes, especially in head and neck region. But KD is also a systemic disease that can involve multiple organs, such as the kidneys and skin. Case presentation We report a 62-year-old Chinese man who presented with paroxysmal cough, enlarged inguinal lymph nodes, recurrent skin itching, and elevated IgE antibodies specific to A. fumigatus. After a comprehensive review, the final diagnosis for this patient was KD with Allergic Bronchopulmonary Aspergillosis (ABPA). Conclusions The age of onset and the location of the lump involved were not characteristic for the illness. This case report described the patient’s diagnosis and treatment process. This case report serves to arouse the attention of multidisciplinary team to explore the potential relationship between KD and ABPA. It will contribute to preventing the misdiagnosis and missed diagnosis of KD.

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The clinicopathological characteristics of Kimura disease in Chinese patients

Zhang

Jiao

2019

Clin Rheumatol

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Acute Limb Ischemia and Coronary Artery Disease in a Case of Kimura’s Disease

Cited by 12 publications

References 6 publications

Stem Cell Therapy in Limb Ischemia: State-of-Art, Perspective, and Possible Impacts of Endometrial-Derived Stem Cells

Stem Cell Therapy in Limb Ischemia: State-of-Art, Perspective, and Possible Impacts of Endometrial-Derived Stem Cells

Kimura disease with Allergic Bronchopulmonary Aspergillosis: a case report

The clinicopathological characteristics of Kimura disease in Chinese patients

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