The clinicopathological characteristics of Kimura disease in Chinese patients

Zhang, Xuehan; Jiao, Yang

doi:10.1007/s10067-019-04752-6

Cited by 30 publications

(67 citation statements)

References 26 publications

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“…KD is a benign inflammatory disease that may mimic other inflammatory and neoplastic conditions such as angiolymphoid hyperplasia with eosinophilia (ALHE), Hodgkin lymphoma, angioimmunoblastic T-cell lymphoma, allergic granuloma, Langerhans cell histiocytosis, Castleman disease and immunoglobulin G4-related disease (IgG4-RD) 1 . There is no reported evidence of malignant transformation 7 .…”

Section: Discussionmentioning

confidence: 99%

“…Kimura disease (KD) is a rare chronic inflammatory disorder of unknown cause. It is characterized by subcutaneous lesions that mainly affect the head and neck region 1 . The exact prevalence of KD is not known; however, since its histopathological diagnosis was ascertained, only 200 cases have been reported 2 , 3 .…”

Section: Introductionmentioning

confidence: 99%

“…The parotid gland is the most common salivary gland involved in KD 1 , 5 , 6 , although its reason is unknown. Nevertheless, a clinicopathologic study of KD involving 21 parotid glands did not show parotid gland as its primary origin but revealed that pathological changes in the gland result from the spread of the disease from the intraparotid lymph nodes (LN) or adjacent soft tissues 6 .…”

Section: Introductionmentioning

confidence: 99%

“…KD can be systemic and may involve multiple organs. Renal involvement is also a well-recognized manifestation that can present simultaneously or months to years later 1 .…”

Section: Introductionmentioning

confidence: 99%

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Kimura Disease with Parotid Swelling and Cervical Lymphadenopathy: A Case Report and Literature Review

Dam¹,

Mohamad²,

Mohamad³

2020

MMJ

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Kimura disease (KD) is a rare chronic benign inflammatory disorder of unknown etiology that is prevalent in Asian males. The head and neck region, especially the parotid glands and cervical lymph nodes, are most commonly affected. Diagnosis is based on clinicopathological features, while radiology findings are nonspecific. Although various treatment strategies have been proposed, there is a high recurrence rate. Combination therapy has been found to produce better results than monotherapy. We present a case of KD with huge parotid and cervical lymph node involvement that was treated with a combination of surgery and corticosteroids administered perioperatively.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…KD can be systemic and may involve multiple organs. Renal involvement is also a well-recognized manifestation that can present simultaneously or months to years later 1 .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Kimura Disease with Parotid Swelling and Cervical Lymphadenopathy: A Case Report and Literature Review

Dam¹,

Mohamad²,

Mohamad³

2020

MMJ

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“…Therapies for Kimura’s disease include surgical excision, steroids, radiation, and immunosuppressive agents (e.g., cyclosporine). Although they can reduce the size of the lesion and delay disease progression, recurrence is common [ 24 , 25 ]. In the present case, the patient was treated with a combination of resection of the lesion and oral steroids.…”

Section: Discussionmentioning

confidence: 99%

Kimura’s disease mimicking thoracic spine dumbbell neurogenic tumor: a case report and literature review

2020

BMC Surg

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Background Kimura’s disease is a rare, benign chronic inflammatory disease of unknown etiology that mostly affects Asians. The disease typically presents as subcutaneous masses in the head or neck region that are predominantly found in the preauricular and submandibular areas. Case presentation A 7-year-old boy presenting with paralysis of both lower extremities and a thoracic spine dumbbell mass was initially diagnosed with a neurogenic tumor, but the pathological and laboratory examinations confirmed the diagnosis of Kimura’s disease. The paralysis symptom disappeared rapidly, but the patient had developed a recurrent mass in the cervical vertebral canal at the 9-month follow-up. Conclusion To our knowledge, no prior published literature has revealed Kimura’s disease cases that mimic dumbbell neurogenic tumors. Here, we report such a case of Kimura’s disease for the first time and provide a brief review of the literature.

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