Acute Citrulline-Malate Supplementation and High-Intensity Cycling Performance

Cunniffe, Brian; Papageorgiou, Maria; O’Brien, Barbara C.; Davies, Nathan; Grimble, G.; Cardinale, Marco

doi:10.1519/jsc.0000000000001338

Cited by 36 publications

(40 citation statements)

References 27 publications

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“…Similarly, a recent trial of a pre-workout supplement which compared 3 supplements; one containing BCAA’s, creatine, caffeine and a 6 g dose of CM; one containing the same (but without caffeine); and a placebo, failed to find any significant improvement in loss of force during resistance exercise from either supplement [ 30 ]. In contrast, CM was effective in retaining muscle power measured by counter measure jump in runners following a marathon Martinez-Sanchez et al [ 29 ] but not at retaining peak power following maximal cycle sprints in well-trained cyclists, [ 20 ] these results suggest the effectiveness of CM to retain power may be dependent exercise modality.…”

Section: Discussionmentioning

confidence: 97%

Citrulline malate supplementation does not improve German Volume Training performance or reduce muscle soreness in moderately trained males and females

Chappell

Allwood

Johns

et al. 2018

Journal of the International Society of Sports Nutrition

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BackgroundUse of supplements to aid performance is common practice amongst recreationally active individuals, including those without a sufficient evidence base. This investigation sought to assess whether acute supplementation with 8 g of citrulline malate (CM) (1.11: 1 ratio) would improve anaerobic performance.MethodsA randomised double blind placebo control trial was employed, using a counterbalanced design. We recruited recreationally active men and women to take part in an isokinetic chair protocol, based on German Volume Training (GVT) whereby participants attempted to perform 10 sets of 10 repetitions against a force representing 70% of their peak concentric force.ResultsThe number of repetitions achieved over the course of the GVT was 94.0 ± 7.9 and 90.9 ± 13.9 for placebo and CM respectively. There was no significant difference between the placebo and CM treatment for number of repetitions (P = 0.33), isometric (P = 0.60), concentric (P = 0.38), or eccentric (P = 0.65) peak force following the GVT. Total muscle soreness was significantly higher in the CM compared to the placebo treatment following the GVT protocol over 72 h (P = 0.01); although this was not accompanied by a greater workload/number of repetitions in the CM group.ConclusionsWe conclude that an acute dose of CM does not significantly affect anaerobic performance using an isokinetic chair in recreational active participants. Practical implications include precaution in recommending CM supplementation. Coaches and athletes should be aware of the disparity between the chemical analyses of the products reviewed in the present investigation versus the manufacturers’ claims.Electronic supplementary materialThe online version of this article (10.1186/s12970-018-0245-8) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 97%

Citrulline malate supplementation does not improve German Volume Training performance or reduce muscle soreness in moderately trained males and females

Chappell

Allwood

Johns

et al. 2018

Journal of the International Society of Sports Nutrition

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“…Cutrufello et al 26) reported that a single dose of 6 g of Cit supplementation prior to exercise was ineffective in improving repetitive exercise performance in male and female members of intercollegiate athletic teams. Cunniffe et al 22) reported that acute supplementation of 12 g of CM 60 min prior to maximal cycle sprints did not enhance acute ergogenic effects in well-trained males. Wilkerson et al 34) reported that acute dietary supplementation with beetroot juice did not significantly improve 50-mile timed trial performance in welltrained cyclists.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies showed that single CM supplementation of 8 g enhanced high-intensity anaerobic exercise performance [17][18][19] , and Cit supplementation of 2.4 or 6 g/day for 1 week enhanced aerobic cycling exercise performance 20,21) . On the other hand, single CM (6 -12 g) or Cit (6 g) supplementation showed no effect on exercise performance [22][23][24][25][26] . Thus, to date, only two studies have reported positive effects on exercise performance using a low dose (< 3 g) of Cit supplementation 20,27) .…”

Section: Introductionmentioning

confidence: 87%

Effect of L-citrulline intake on intermittent short-time high-intensity exercise performance in male collegiate track athletes

Terasawa

Nakada

2019

JPFSM

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Enhanced exercise performance and anti-fatigue effects following L-citrulline (Cit) intake have been reported in resistance training and endurance exercise, but not in intermittent short-time high-intensity exercise. Therefore, the effect of Cit intake on intermittent short-time high-intensity exercise performance in collegiate athletes was investigated. A double-blind, placebo-controlled crossover trial was performed using nine male collegiate track athletes (age 20.9 ± 1.6 years). Each participant ingested either Cit or a placebo (3 g [grams]/day) for 7 days and underwent Wingate test using a bicycle ergometer on days 0 and 7 performed three times using a pedaling load of 7.5% of the participant's weight for 30 s (seconds) at full power. As for the results, Cit intake significantly increased the change in mean power output, pedaling speed per 5 s, and power output per 5 s (Δday 7 -0) during pedaling as well as the change in oxygen consumption derived by analysis of expired gas. The amount of change in the rate of perceived exertion during exercise significantly decreased, and the amount of change in serum nitrite/nitrate (NOx) (Δday 7 -0) post-exercise was significantly increased compared to that of pre-exercise by Cit intake. These results suggested that Cit intake of 3 g/day for 7 days may have enhanced exercise performance and anti-fatigue effects on intermittent short-time highintensity exercise in male collegiate track athletes.

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“…Studi Brian Cunniffe (2016) menunjukkan bahwa suplementasi 12 g sitrulin dalam 400 ml atau lemon cordial tidak memberikan manfaat ergogenic pada atlet. 13 Hal ini sejalan dengan penelitian Cutrufello yang menyatakan bahwa pemberian jus semangka dengan kandungan sitrulin 1 gr dan 6 gr tidak menunjukkan perubahan dalam kinerja aerobik dan fisiologis. Respon sitrulin dalam latihan anaerobik diketahui tetapi mekanisme sitrulin dalam latihan aerobik tidak jelas.…”

Section: Perbedaan Indeks Kelelahan Otot Subjek Penelitian Sebelum Daunclassified

PENGARUH PEMBERIAN JUS SEMANGKA KUNING (Citrullus lanatus) TERHADAP KELELAHAN OTOT ANAEROBIK PADA ATLET SEPAKBOLA

et al. 2019

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Background : Muscle fatigue in anaerobic activity occured, when athletes have high intensity activities. The accumulation of lactic acid in muscle and blood could inhibit muscle contraction caused low concentration and performance. Sitrulin in yellow watermelon (Citrullus lanatus) juice can delay muscle fatigue in anaerobic activity. Objective : To know the effect of Yellow Watermelon Juice (Citrullus lanatus) To Anaerobic Muscle Fatigue Index Athletes. Methods : This study used quasi experimental design with a pre-post test design group control design. The fourteen athletes who were randomly divided into control groups and treatment groups. The control group was given a placebo and the treatment group was given a 500 ml watermelon juice with a dose of 1,8gr of sitrulin during seven days. Yellow watermelon (Citrullus lanatus) juice are given 60 minutes before the test done. Anaerobic muscle fatigue in soccer athletes were measured using a RAST (Running-based Anaerobic Sprint Test) by calculating the Muscle Fatigue Index. Data were analyzed by Independent t-test. Results : In this study there was an increase category of muscle fatigue index from good category (0.21-3.31) to very good category (<0.21), although both control and treatment group not significant different statistically (p = 0,532). The mean initial muscle fatigue index of the treatment and control group respectively (0.1157 ± 0.05) and (0.1486 ± 0.65). The mean final muscle fatigue index of the treatment and control group respectively (0.1229 ± 0.04) and (0.1371 ± 0.03). Conclusion : The adduction of yellow watermelon juice (citrullus lanatus) during seven days did not affect the reduction of anaerobic muscle fatigue (p = 0,532).

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Acute Citrulline-Malate Supplementation and High-Intensity Cycling Performance

Cited by 36 publications

References 27 publications

Citrulline malate supplementation does not improve German Volume Training performance or reduce muscle soreness in moderately trained males and females

Citrulline malate supplementation does not improve German Volume Training performance or reduce muscle soreness in moderately trained males and females

Effect of L-citrulline intake on intermittent short-time high-intensity exercise performance in male collegiate track athletes

PENGARUH PEMBERIAN JUS SEMANGKA KUNING (Citrullus lanatus) TERHADAP KELELAHAN OTOT ANAEROBIK PADA ATLET SEPAKBOLA

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