2005
DOI: 10.1016/j.humimm.2005.01.009
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Acute and Hyperacute Humoral Rejection in Kidney Allograft Recipients Treated with Anti-Human Thymocyte Antibodies

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Cited by 30 publications
(15 citation statements)
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“…Some of the targets of ATG, such as the HLA Ag, may also be expressed on other cell types, and may become targets of ATG cytotoxicity. It has already been suspected in a few kidney and heart recipients that ATG treatment can lead to C4d deposition in the graft, and possibly to graft rejection [23,24]. In our patients, the use of ATG containing anti-HLA-A3 Ab was never associated with severe reactions, graft dysfunction, or rejection.…”
Section: Discussionsupporting
confidence: 44%
“…Some of the targets of ATG, such as the HLA Ag, may also be expressed on other cell types, and may become targets of ATG cytotoxicity. It has already been suspected in a few kidney and heart recipients that ATG treatment can lead to C4d deposition in the graft, and possibly to graft rejection [23,24]. In our patients, the use of ATG containing anti-HLA-A3 Ab was never associated with severe reactions, graft dysfunction, or rejection.…”
Section: Discussionsupporting
confidence: 44%
“…151 Prophylactic ATG (RATG and equine ATG) has been reported in 1 study to induce acute and hyperacute AMR in nonsensitized patients with renal allografts. 152 Although there have been successful cases in which AMR has been treated successfully with ATG in combination with other immunosuppressive therapy, this class of drugs requires testing as part of a randomized trial in AMR. 108,143,[153][154][155][156] …”
Section: Anti-lymphocyte Globulinsmentioning
confidence: 99%
“…These technologies have gained wide acceptance for tissue typing and immunology (18). Their use for infectious disease control is expanding, even in low-resource countries (19).…”
mentioning
confidence: 99%