Actualización de la distribución de especies del género Haemagogus (Díptera: Culicidae) en la región Caribe colombiana

Maestre‐Serrano, Ronald; Cochero, Suljey; Bello, Betsy; Ferro, C.

doi:10.7705/biomedica.v33i0.706

Cited by 3 publications

(1 citation statement)

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“…La cepa Lbn mostró una homología del 98% para L. (V.) braziliensis coincidiendo con Satow et al (11) . El amplicón tuvo 536 pb (cinetoplasto) para la misma especie se reportó un amplicón de 599 pb (citocromo B) (12) . Los macrófagos peritone-Figura 2.…”

Section: Discussionunclassified

Expresión transcripcional de receptores tipo Toll y citoquinas proinflamatorias en macrófagos infectados con <i>Leishmania braziliensis</i> nativa

Torres Gonzales,

Alzamora-Gonzales

2024

An Fac med

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Introduction. The Toll-like receptor (TLR) interacting with the promastigote of Leishmania spp. determines the cellular activation pathway. Objective. To determine the transcriptional expression of TLR-3, TLR-4, TLR-9, IL-12 and TNF-α in macrophages infected with a native strain of L. braziliensis (Lbn). Materials and Methods. Identification of Lbn was performed by qPCR for kinetoplast DNA sequences. Mouse peritoneal macrophages were infected with promastigotes (MI) and nitric oxide (NO) production was measured; transcript levels for TLRs and cytokines were quantified by qRT-PCR. Results. Lbn showed 96% homology to L. braziliensis. High ON production was observed in IMs at 2 h; significant transcriptional expression especially of TLR-3 and TLR-9, which corresponded with expression for cytokines. Conclusions. Lbn strongly activated macrophages via endosomal TLRs, which can be applied in the design of agonists to treat the disease.

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Section: Discussionunclassified

Expresión transcripcional de receptores tipo Toll y citoquinas proinflamatorias en macrófagos infectados con <i>Leishmania braziliensis</i> nativa

Torres Gonzales,

Alzamora-Gonzales

2024

An Fac med

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Prevalence of Mosquito Populations in the Caribbean Region of Colombia with Important Public Health Implications

et al. 2022

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Mosquito studies are important for understanding their role in the transmission of pathogens including arboviruses, parasites, and protozoa. This study characterized the prevalence of Culicidae fauna in rural and peri-urban areas with human populations in the Colombian Caribbean region to establish the risk of transmission of mosquito-borne pathogens. From 2016 to 2017, adult mosquitos were collected in Turbaco (Bolívar), Sabanalarga (Atlántico) and Pueblo Bello (Cesar). The collections in rural areas were in the forest fragments using CDC, Shannon, and human bait traps. In peri-urban areas, Prokopack aspirator collections were used inside households. Entomological and ecological indicators were also calculated. A total of 11,566 mosquito specimens, from 13 genera and 63 species, were collected. The forests fragments of Sabanalarga and Turbaco had the highest species abundance and richness. Turbaco had the highest adult Aedes aegypti index. Arbovirus vectors were among the identified species, including Ae. aegypti, Culex quinquefasciatus, Haemagogus janthinomys, Sabethes chloropterus, Aedes angustivittatus, Mansonia titillans, Coquillettidia venezuelensis and the subgenera Culex Melanoconion. Overall, the diversity and abundance of mosquitoes present in these municipalities establish a potential disease transmission risk by these vectors.

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Data-driven identification of potential Zika virus vectors

Evans

Dallas

Han

et al. 2017

eLife

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Zika is an emerging virus whose rapid spread is of great public health concern. Knowledge about transmission remains incomplete, especially concerning potential transmission in geographic areas in which it has not yet been introduced. To identify unknown vectors of Zika, we developed a data-driven model linking vector species and the Zika virus via vector-virus trait combinations that confer a propensity toward associations in an ecological network connecting flaviviruses and their mosquito vectors. Our model predicts that thirty-five species may be able to transmit the virus, seven of which are found in the continental United States, including Culex quinquefasciatus and Cx. pipiens. We suggest that empirical studies prioritize these species to confirm predictions of vector competence, enabling the correct identification of populations at risk for transmission within the United States.DOI: http://dx.doi.org/10.7554/eLife.22053.001

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Actualización de la distribución de especies del género Haemagogus (Díptera: Culicidae) en la región Caribe colombiana

Cited by 3 publications

References 10 publications

Expresión transcripcional de receptores tipo Toll y citoquinas proinflamatorias en macrófagos infectados con <i>Leishmania braziliensis</i> nativa

Expresión transcripcional de receptores tipo Toll y citoquinas proinflamatorias en macrófagos infectados con <i>Leishmania braziliensis</i> nativa

Prevalence of Mosquito Populations in the Caribbean Region of Colombia with Important Public Health Implications

Data-driven identification of potential Zika virus vectors

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