Data-driven identification of potential Zika virus vectors

Evans, Michelle V.; Dallas, Tad; Han, Barbara A.; Murdock, Courtney C.; Drake, John M.

doi:10.7554/elife.22053

Cited by 72 publications

(75 citation statements)

References 257 publications

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“…Recent studies showed that diverse ecological and evolutionary features describing intrinsic organismal characteristics can be combined to predict species suitable for disease transmission (Olival et al ., ). For example, based on traits of species, recent studies used supervised machine learning algorithms to identify and prioritize rodent reservoirs of zoonotic diseases (Han et al ., ), bat species hosting filoviruses (Han et al ., ), mosquito vectors of Zika virus (Evans et al ., ), and suitable tick vectors from the genus Ixodes (Yang & Han, ). Future research should explore species traits (e.g.…”

Section: Ecological Modelling Of Cwd Spread Zoonotic Potential and mentioning

confidence: 99%

The ecology of chronic wasting disease in wildlife

et al. 2019

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Prions are misfolded infectious proteins responsible for a group of fatal neurodegenerative diseases termed transmissible spongiform encephalopathy or prion diseases. Chronic Wasting Disease (CWD) is the prion disease with the highest spillover potential, affecting at least seven Cervidae (deer) species. The zoonotic potential of CWD is inconclusive and cannot be ruled out. A risk of infection for other domestic and wildlife species is also plausible. Here, we review the current status of the knowledge with respect to CWD ecology in wildlife. Our current understanding of the geographic distribution of CWD lacks spatial and temporal detail, does not consider the biogeography of infectious diseases, and is largely biased by sampling based on hunters' cooperation and funding available for each region. Limitations of the methods used for data collection suggest that the extent and prevalence of CWD in wildlife is underestimated. If the zoonotic potential of CWD is confirmed in the short term, as suggested by recent results obtained in experimental animal models, there will be limited accurate epidemiological data to inform public health. Research gaps in CWD prion ecology include the need to identify specific biological characteristics of potential CWD reservoir species that better explain susceptibility to spillover, landscape and climate configurations that are suitable for CWD transmission, and the magnitude of sampling bias in our current understanding of CWD distribution and risk. Addressing these research gaps will help anticipate novel areas and species where CWD spillover is expected, which will inform control strategies. From an ecological perspective, control strategies could include assessing restoration of natural predators of CWD reservoirs, ultrasensitive CWD detection in biotic and abiotic reservoirs, and deer density and landscape modification to reduce CWD spread and prevalence.

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Section: Ecological Modelling Of Cwd Spread Zoonotic Potential and mentioning

confidence: 99%

The ecology of chronic wasting disease in wildlife

et al. 2019

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“…Cx. quinquefasciatus has been identified by predictive models as a potential vector for Zika virus [132], as have Sabethes and Haemagogus spp . [133].…”

Section: Resultsmentioning

confidence: 99%

Arbovirus Vectors of Epidemiological Concern in the Americas: A Scoping Review of Entomological Studies on Zika, Dengue and Chikungunya Virus Vectors

Jones

Kulkarni

Davidson

et al. 2019

Preprint

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27 Background 28 Three arthorpod-borne viruses (arboviruses) causing human disease have been the focus 29 of a large number of studies in the Americas since 2013 due to their global spread and 30 epidemiological impacts: Zika, dengue, and chikungunya viruses. A large proportion of 31 infections by these viruses are asymptomatic. However, all three viruses are associated with 32 moderate to severe health consequences in a small proportion of cases. Two mosquito species, 33 Aedes aegypti and Aedes albopictus, are among the world's most prominent arboviral vectors, 34 and are known primary vectors for all three viruses in the Americas. 35 Objectives 2 36 This review summarizes the state of the entomological literature surrounding the biology 37 and ecology of vectors of Zika, dengue and chikungunya viruses and factors affecting virus 38 transmission. The rationale of the review was to elucidate consensus and discord between 39 studies, and guide future research based on identified knowledge gaps. 40 Results 41 A total of 196 studies were included in the scoping review after initial screening and 42 subsequent exclusion of out-of-scope studies, secondary data publications, duplicate records, and 43 studies unavailable in English language. 44 Key findings 45 Temperature and humidity have the strongest impact on mosquito distribution and 46 dynamics, development of immatures and arborviral infection rates. Low socioeconomic status 47 and related factors, including poor infrastructure, inconsistent access to water, and high 48 household resident density, have been consistently associated with arbovirus vector occurrence. 49 Effects of interspecific competition on arboviral vector species is currently poorly understood. 50 Vector competence for Zika virus is well established for Ae. aegypti and Ae. albopictus. 51 Information on Zika virus vector transmission dynamics is sparse in contrast to the wealth of 52 research available for dengue and chikungunya viruses. 53 Conclusions 54Based on the internationally recognized urgency of Zika virus infection as a public health 55 concern, further research on arbovirus vectors and transmission dynamics is of pressing need. 56 57

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“…Furthermore, based on a data-driven model linking mosquito vector species and vector-virus traits, Evans et al (2017) have predicted that as many as 35 different mosquito species could be vectors for ZIKV.…”

Section: Keep An Open Mindmentioning

confidence: 99%

Linking Only Aedes aegypti with Zika Virus Has World-Wide Public Health Implications

Hunter

2017

Front. Microbiol.

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Data-driven identification of potential Zika virus vectors

Cited by 72 publications

References 257 publications

The ecology of chronic wasting disease in wildlife

The ecology of chronic wasting disease in wildlife

Arbovirus Vectors of Epidemiological Concern in the Americas: A Scoping Review of Entomological Studies on Zika, Dengue and Chikungunya Virus Vectors

Linking Only Aedes aegypti with Zika Virus Has World-Wide Public Health Implications

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