Actoprotective effect of ginseng: improving mental and physical performance

Oliynyk, Sergiy; Oh, Seikwan

doi:10.5142/jgr.2013.37.144

Cited by 45 publications

(33 citation statements)

References 126 publications

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“…It has been extensively studied over many years, and a large literature on its many diverse biological actions exists. Though some reviews have concluded that ginseng can promote both physical and mental performance and increase resistance to imposed stress (Oliynyk & Oh, 2013), it is important to recognize that much of the research in this area has been described as generally poor (Choi et al, 2013). The same conclusion might be reached for most of the supplements in this category.…”

Section: Promoting Adaptations To Trainingmentioning

confidence: 84%

Dietary Supplements for Aquatic Sports

Derave¹,

Tipton²

2014

International Journal of Sport Nutrition and Exercise Metabolism

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Many athletes use dietary supplements, with use more prevalent among those competing at the highest level. Supplements are often self-prescribed, and their use is likely to be based on an inadequate understanding of the issues at stake. Supplementation with essential micronutrients may be useful when a diagnosed deficiency cannot be promptly and effectively corrected with food-based dietary solutions. When used in high doses, some supplements may do more harm than good: Iron supplementation, for example, is potentially harmful. There is good evidence from laboratory studies and some evidence from field studies to support health or performance benefits from appropriate use of a few supplements. The available evidence from studies of aquatic sports is small and is often contradictory. Evidence from elite performers is almost entirely absent, but some athletes may benefit from informed use of creatine, caffeine, and buffering agents. Poor quality assurance in some parts of the dietary supplements industry raises concerns about the safety of some products. Some do not contain the active ingredients listed on the label, and some contain toxic substances, including prescription drugs, that can cause health problems. Some supplements contain compounds that will cause an athlete to fail a doping test. Supplement quality assurance programs can reduce, but not entirely eliminate, this risk.

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Section: Promoting Adaptations To Trainingmentioning

confidence: 84%

Dietary Supplements for Aquatic Sports

Derave¹,

Tipton²

2014

International Journal of Sport Nutrition and Exercise Metabolism

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“…It is traditionally considered as one of the most valuable herbal Adapted from Oh et al (2007) with permission medicines in Far East Asia because of its many health-promoting effects. The root of ginseng is traditionally used to boost mental efficiency, combat weakness, relieve fatigue and normalise body functions and systems that are compromised by stress Oliynyk & Oh, 2013). Scientific data have also established the usefulness of Korean ginseng in the boosting of sex hormone levels of several experimental models (Kopalli et al, 2015).…”

Section: Kore An Red G In S Eng (Pa N a X Ginseng Me Yer )mentioning

confidence: 99%

Plants in the management of male infertility

Onuah

Singh

2020

Andrologia

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This review attempts to collate existing data and provide the perspectives for future studies on the effects of plants on the male gonads. For many of these medicinal plants such as Lepidium meyenii, Rupus coreanus, Tribulus terrestres, Panax ginseng, Petasites japonicas, Apium graveolens, Eurycoma longifólia, Pedalium murex, Corchorus depressus, Mucuna pruriens, Astragalus membranaceus, Nigella sativa, Crataegus monogyna, Fagara tessmannii, Phaleria macrocarpa, Anacyclus pyrethrum, Cynomorium songaricum and Morinda officinalis, the mechanism of actions of their active principles and crude extracts has been shown in both laboratory animals, in vitro, and human studies, and includes their antioxidant, anti‐inflammatory, spermatogenesis‐inducing, aphrodisiac, smooth muscle relaxing and androgenic properties. Several active chemical leads including glucosinolates, anthocyanins, protodioscin, ginsenosides, sesquiterpenes, phyto‐oestrogens, quassinoids, diosgenin, thymoquinone, proanthocyanidins and bajijiasu isolated from these plants are known to have target effects on the testis, but efforts have been limited in their application at the clinical level. There still appear to be many more extracts of medicinal plants that have not been characterised to determine the phytochemicals unique to them that have target effects on the gonads. Further, collaborative efforts at isolating pro‐drug candidates from medicinal plants for studies at the molecular, cellular and clinical level towards elucidating their mechanisms of action on the testes are therefore warranted in the light of the current male fertility crisis.

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“…Это обусловлено структурной и функциональной связью этих соединений со стероидами. Например, многие из них принадлежат к семейству стероидных сапонинов [46,47]. Последние благодаря своей структуре имеют множество физиологических активностей.…”

Section: мультифитоадаптоген -жидкий экстрактunclassified

Immunoadhesive regulation using multiphytoadaptogene for spontaneous hepatocarcinomas prevention

Бочаров

Бочарова

Карпова

et al. 2018

Rossijskij bioterapevtičeskij žurnal

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The purposeof this investigation was to evaluate the efficacy of correcting the LFA-1 and Mac-1 leukocyte integrins expression on peripheral blood cells as well as IL-6 and IL-10 serum levels using liquid form multiphytoadaptogene preventive application for hepatocarcinomas incidence suppression and life-span increase of CBA inbreed mice.Materials and methods.The study was carried out on 439 males of inbred CBA mouse strain (subline CBA/LacY). The experimental mice received 10 % liquid form multiphytoadaptogene complex (MPAC) solution in drinking water during the first month of life including the final time period of liver differentiation (preventive administration). MPAC is the standardized herbal formula composed of 40 plant extracts components including adaptogenes Panax ginseng, Eleutherococcus senticosus, Rhodiola rosea, as well as compounds with phenolic structure (flavonoids, triterpene glycosides, etc). Anti-mutagenic, anti-oxidant, immunomodifying activities of MPAC were demonstrated. The CD11a and CD11b antigens expressions on peripheral blood cells were analyzed by indirect immunofluorescence reaction, serum cytokines IL-6 and IL-10 concentrations were determined by enzyme-linked immunosorbent assay as well as the liver tissue morphology were analyzed at the age of 4, 8, 22 months. Tumor incidence and volumes were evaluated at the age of 8 and 22 months. Motor activity and physical status (body weight, coat state) were estimated in the ontogenesis. The average life-span and survival median was analyzed by the Kaplan–Meier method. Statistical analysis was performed with the program STATISTICA 6.0.Results.Inhibited expression of LFA-1 and Mac-1 leukocyte integrins on peripheral blood cells as well as elevated IL-6 and IL-10 serum levels, high incidence of liver tumors (100 % of mice-males), their high number and big sizes in the late period of postnatal ontogenesis in CBA high-cancer inbrede mice, also as life-span not reaching two years was demonstrated. At the same time plural tumor-infiltrating limphocytes were not found. Short-term MPAC preventive administration (during the first month of mouse life occupying the final differentiation period of liver tissue genetically predisposal to hepatoms incidence) revealed the long-term heterotypic adhesion molecules leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) up-regulated expression, providing the contact interactions of immune effectors and cancer cells. The events shown is able to enhance the anti-tumor activity of immune reactions including spontaneous hepatocarcinomas lymphocytes infiltration and destruction of tumor tissue. As a result, the hereditary tumors incidence, their number and sizes were reduced as well as life-span and life quality of animals were improved.Conclusion.Up-regulated leukocyte integrins expression on peripheral blood cells, reduced IL-6 and IL-10 serum levels accompanied by tumors lymphocyte infiltration and destruction using MPAC preventive administration is essential for tumor incidence down-regulation. The herbal formula with multiple components is capable to controle anti-tumor immune reactions, as well as the life-span and life quality of high-cancer animals. Hence, the regulation of adhesion violations involved in tumor incidence can be cancer preventive.

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Actoprotective effect of ginseng: improving mental and physical performance

Cited by 45 publications

References 126 publications

Dietary Supplements for Aquatic Sports

Dietary Supplements for Aquatic Sports

Plants in the management of male infertility

Immunoadhesive regulation using multiphytoadaptogene for spontaneous hepatocarcinomas prevention

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