Active Compounds and Bacteria Harbouring Capacity of Lichens and Its Medicinal Use in Bacterial and Cancer Infections

Kumar, Narendra; Khurana, Shruti

doi:10.1007/978-981-13-8499-8_15

Cited by 2 publications

(1 citation statement)

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“…Fumarprotocetraric acid has been found in many Cladonia species such as C. foliaceae, C. verticillaris, C. furcata, C. rangiformis, and C. rangiferina. (Laundon 1971;Yilmaz et al 2004;De Barros et al 2014;Narendra and Khurana, 2019). According to the Farkas et al research, the concentration of fumarprotocetraric acid of C. foliacea acetone extract varied between 2.26 and 5.81 mg g -1 in winter collected samples.…”

Section: Discussionmentioning

confidence: 97%

Comparative analyses of antioxidant, cytotoxic, and anti-inflammatory activities of different Cladonia species and determination of fumarprotocetraric acid amounts

Kocakaya

Karatoprak

2021

Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi

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The study aimed to determine the biological activities of 70% methanol extracts of nine Cladonia species from Turkey. The chemical composition was analyzed via spectrophotometric and chromatographic (HPLC) techniques. DPPH • (1,1-diphenyl-2picrylhydrazyl) and ABTS +• (2,2'-azino-bis (3-ethylbenzothiazoline-6sulphonic acid) radical scavenging activities, inhibition of βcarotene/linoleic acid co-oxidation, and cytotoxicity on A549 and COLO205 cell lines were studied. Anti-inflammatory activity was assessed on the Raw 264.7 mouse macrophage cell line by determining nitric oxide (NO) levels. Among the studied Cladonia species Cladonia firma was found the most active extract in ABTS +• test system (2.58±0.04 mmol/L/Trolox) and also in the cytotoxicity and antiinflammatory experiments. Cladonia pocillum, Cladonia rangiformis, and Cladonia foliaceae were also found to be active. Fumarprotocetraric acid amounts are between 1.89-23.82 mg gextract -1 and fumarprotocetraric acid content did not show linearity with biological activities. It has been proved with this study that lichens traditionally used in treatment have as much biological activity as plants and can be evaluated in pharmaceuticals and cosmetics.

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Section: Discussionmentioning

confidence: 97%