Action of diosgenin and homoeopathic pathogenesis of Dioscorea villosa

Naskar, Kisor Kumar; Mishra, Ompriya

doi:10.4103/0974-7168.200845

Cited by 5 publications

(2 citation statements)

References 2 publications

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“…Yam contains products such as alkaloids (saponin and sapogenin) and proteins (dioscorin and diosgenin) which can cause side effects in humans and animals such as inflammations, allergic reactions, kidney problems, and interference with the metabolic system [57,58]. However, these same properties of the yam plant are exploited in medicine for the treatment and management of conditions such as allergies, metabolic disorders, hypertension, inflammations, and hormonal irregularities [58][59][60]. Yam has been used in traditional medicine in Africa and among the Chinese and other Asiatic people to treat diseases like diabetes, to increase coronary circulation, and to prevent hypercholesterolemia [55,61,62].…”

Section: Tablementioning

confidence: 99%

State of the Art of Yam Production

Wumbei¹,

Gautier²,

Kwodaga³

et al. 2023

Advances in Root Vegetables Research

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Yam is a labor-intensive and weed-sensitive food crop. The labor-intensive nature of the yam means that the production process requires the attention of the farmer all year round. However, the dwindling labor situation and the proliferation of weeds have forced farmers to think of modern ways of controlling weeds on their farms, that is, the adoption of chemical (herbicides) weed control. Even though the adoption of these chemicals has no doubt brought relief to the farmers and has resulted in increased yam production over the years, it has also brought in its wake, negative externalities of environmental pollution, human health effects, and food quality issues. The study was thus designed to investigate how yam is produced, the human and environmental health effects of how yam is produced, and food quality effects of how yam is produced. This was done through literature review, and field and laboratory experiments. It was revealed that, in recent years, new innovations have been introduced in yam production, the manner in which farmers handle herbicides in their yam production process exposes them to high doses of pesticides, thereby endangering their lives. The study findings also suggest that the use of herbicides in yam production does not affect the quality of the yam.

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Section: Tablementioning

confidence: 99%

State of the Art of Yam Production

Wumbei¹,

Gautier²,

Kwodaga³

et al. 2023

Advances in Root Vegetables Research

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“…Besides this gastro-intestinal sphere, it also has genito-urinary, cardio-vascular, peripheral neurological and inflammatory manifestations [22,33] . Behind all these pathological conditions, the active ingredient diosgenin seems to have important role by its altered cholesterol metabolism which might be the underlying pathological essence of homoeopathic pathogeneses of Dioscorea [34] . [22,33] Extensive proving of Dioscorea was done by Dr. A. M. Cushing, Dr. J. U.…”

Section: Introductionmentioning

confidence: 99%

Homoeopathic pathogeneses of dioscorea villosa and the role of dysregulated cholesterol metabolism by the action of diosgenin: A review

Naskar¹,

Mishra²

2018

Int. J. Homoeopathic Sci.

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Background: Dioscorea villosa (Dioscorea) is one of the important homoeopathic medicines for gastro-intestinal, sexual, cardiovascular, peripheral inflammatory or neurological affections. Diosgenin is the primary active ingredient of Dioscorea which is responsible for all possible revealed actions of this plant. Objective: To know background patho-physiology for development of homoeopathic pathogeneses of Dioscorea.Method & Result: Homoeopathic pathogeneses of Dioscorea, have been collected from 11 homoeopathic books and 1article. A comprehensive online search on different actions of diosgenin and dioscorea itself (18 research and 5 reviews), for hyperactivity of cholesterol as well as lipid metabolism in different patho-physiological fields (14 research and 17 reviews), along with other related articles have been assessed by using PubMed and other sources and appraised according to their research outcome. Conclusion:By the action of diosgenin, altered or dysregulated cholesterol metabolism might have a background patho-physiological role to develop homoeopathic pathogeneses of Dioscorea.

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