Acrylonitrile-Induced Synthesis of Polyvinyl Alcohol-Stabilized Selenium Nanoparticles

Abstract

A new simple wet chemical method has been developed to synthesize selenium nanoparticles (size 50 to 100 nm), by reaction of sodium selenosulphate precursor with acrylonitrile monomer, under ambient conditions. Polyvinyl alcohol has been used to stabilize the selenium nanoparticles. The synthesized nanoparticles can be separated from their sol by using a high-speed centrifuge and can be redispersed in aqueous medium with an ultrasonicator. UV-visible optical absorption spectroscopy, X-ray powder diffraction, energy dispersive X-ray analysis, differential scanning calorimetry, atomic force microscopy, scanning electron microscopy, and transmission electron microscopy techniques have been used to characterize the synthesized selenium nanoparticles. Gas chromatography-mass spectrometry analysis has shown formation of -hydroxy propionitrile as a byproduct. On the basis of these findings, a mechanism has been proposed for the formation of selenium nanoparticles and -hydroxy propionitrile.

Selenium nanoparticles: a review on synthesis and biomedical applications

“…Similarly, by changing the stabilising agent to polysorbate 20, Vahdati et al 20 obtained a characteristic UV absorption peak at 265 nm consistent with a previous report but with a much smaller particle size in the range of 35–45 nm in comparison to that obtained by using PVA or chitosan. Likewise, Shah et al 68 also used PVA as the stabilizer to obtain SeNPs of 50–100 nm size. The authors for the first time reported that sodium selenosulphate responded to the acrylonitrile monomer, forming SeNPs.…”

An Organic Acid-induced Synthesis and Characterization of Selenium Nanoparticles

“…Reduction method is the most popular method for selenium nanoparticle preparation, which includes chemical reduction [13], γ-radiolytic reduction [14], bacterial reduction [15], and so forth. However, some literature on the formation of nanoselenium via oxidation method, such as reaction of selenourea with hydroxyl radical [16], electrochemical oxidation of selenide [17], and reaction of sodium selenosulphate with acrylonitrile [18], also exists.…”

Selenium Nanoparticle Enhanced Photodynamic Therapy against Biofilm forming Streptococcus mutans

“…GNP has remarkable surface plasmon resonance for imaging and fluorescence enhancing or quenching of attached drugs or dyes. [36][37] This is first study where Selenium nanoparticle are used to enhance photodynamic effect of TBO. The current study focuses on the use of PDT performed with TBO in presence of SeNP, since a better understanding of S. mutans photo inactivation is an important issue in Dentistry.…”