Acinetobacter Baumannii Nosocomial Infections

Abstract

Nosocomial infections caused by strains Acinetobacter baumannii strands are a growing clinical problem.The occurrence of multidrug-resistant strands is observed and that limits the ways of therapy considerably. the aim of the study was to determine the rate of infection and susceptibility spectrum of the species Acinetobacter baumannii isolated from patients treated at Maria Skłodowska-Curie Memorial Hospital in Zgierz with particular emphasis on surgical wards. Materials and methods. The material consisted of Acinetobacter baumannii isolates were obtained from samples of materials from patients treated at Maria Skłodowska-Curie Memorial Hospital in Zgierz from January to December 2011. Isolated bacterial strains were cultured at microbiological substrates. Isolates were identified to species using the VITEK 2 GN card (bioMérieux) and Vitek 2 automated system (bioMérieux). Susceptibility towards antibiotics of particular strains was determined by the means of AST NO 93 card. In the case of resistance towards carbapenem, the MIC was marked by E-test with Mueller Hinton substrate. The occurrence of MBL was verified by the means of disc system with Mueller Hinton substrate. Results. We have shown that total number of Acinetobacter baumannii infections at hospital was 140 (10,31% of total results of cultures). Percentage of Acinetobacter baumannii infections at wards: Intensive Care Unit 48%, Surgical Departments 20%, Internal Diseases Department 16%, Neurology 13%, other wards -3%. The susceptibility percentage of Acinetobacter Baumannii against antibiotics: colistin 90%, imipenem 64%, meropenem 43%, ampicillin-sulbactam 28%, amikacin 27%, gentamicin 24%, cefepime 9%, ceftazidime 7%, ciprofloxacin 7% conclusions. Acinetobacter baumannii infections are a significant proportion of nosocomial infections. Most relate to surgical wards and ICUs. Acinetobacter baumannii is resistant against most antibiotics. The highest percentage of sensitivity demonstrated for colistin and carbapenems.

Epidemiological Monitoring of Nosocomial Infections Caused by Acinetobacter Baumannii

“…Dima and colleagues also report that the Acinetobacter species are predominant cause of ventilator-associated pneumonia ( 13 ). Moreover, researchers from Poland showed the results similar to our study, reporting a high percentage of Acinetobacter species as a cause of nosocomial infections in the ICU ( 14 ). Exogenous transmission of Acinetobacter should be considered when infections are endemic and when case rates increase ( 15 ).…”

Multidrug-resistant Acinetobacter baumannii: differential adherence to HEp-2 and A-549 cells

“…Acinetobacter baumannii is an aerobic, non-fermentative Gram-negative coccobacillus that can survive for long periods in the environment [1]. A. baumannii infections are a major cause of hospital-acquired infections worldwide, mainly due to A. baumannii's ability to live under critical situations in this environment [2,3]. Resistance to desiccation and antibiotics [4,5], high production of biofilm on abiotic surfaces, and the adherence to human cells [6][7][8][9] might justify the prevalence of this microorganism in hospitals in outbreaks and endemic situations.…”

Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids

“…E. coli , P. aeruginosa , and S. aureus are most commonly used in clinical studies [ 42 ] . K. pneumoniae and A. baumani are known to cause nosocomial infections and acquire simultaneous resistance mechanisms [ 43 , 44 ]. Bacillus spp.…”