Acetic acid compared with i-scan imaging for detecting Barrett’s esophagus: a randomized, comparative trial

Hoffman, Arthur; Korczynski, Oliver; Tresch, Achim; Hansen, Torsten; Rahman, Farreed; Goetz, Martin; Murthy, Sanjay K.; Galle, Peter R.; Kießlich, Ralf

doi:10.1016/j.gie.2013.07.013

Cited by 40 publications

(27 citation statements)

References 23 publications

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“…In 2 head-to-head studies, acetic acid and I-Scan had similar results in diagnosing intestinal metaplasia (57% vs 66%, P 5 .075) 26 and indigo carmine and NBI were also found to be comparable in detecting HGD and early neoplasia (93% vs 86%, P 5 1). 7 Given their similar clinical efficacy, optical chromoendoscopy offers several practical advantages over traditional dye-based chromoendoscopy, including ease of use, uniformity of the mucosal distribution, and likely shorter procedure times, all without any potential additional risk to the patient.…”

Section: Optical Chromoendoscopymentioning

confidence: 79%

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Advanced Imaging in Barrett's Esophagus

Muthusamy

Kim

Wallace

2015

Gastroenterology Clinics of North America

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Section: Optical Chromoendoscopymentioning

confidence: 79%

“…The few studies that have evaluated FICE and I-SCAN were used in conjunction with acetic acid chromoendoscopy. 25,26 Therefore, NBI is the focus of the following discussion.…”

Section: Optical Chromoendoscopymentioning

confidence: 99%

Advanced Imaging in Barrett's Esophagus

Muthusamy

Kim

Wallace

2015

Gastroenterology Clinics of North America

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“…I-scan, by manipulating the red, blue and green color of light, enhances vascular and mucosal structures. Its use in combination with acetic acid has shown a higher diagnostic yield for IM when compared to standard random biopsies (44).…”

Section: Diagnosis Of Bementioning

confidence: 99%

Optimizing the diagnosis and therapy of Barrett’s esophagus

2017

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“…i-Scan improves detection of BE compared with standard white light endoscopy, particularly when combined with zoom imaging (figure 1). 38…”

Section: Endoscopic Techniquesmentioning

confidence: 99%

Monitoring the premalignant potential of Barrett's oesophagus'

Graham

Lipman

Sehgal

et al. 2016

Frontline Gastroenterol

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The landscape for patients with Barrett's oesophagus (BE) has changed significantly in the last decade. Research and new guidelines have helped gastroenterologists to better identify those patients with BE who are particularly at risk of developing oesophageal adenocarcinoma. In parallel, developments in endoscopic image enhancement technology and optical biopsy techniques have improved our ability to detect high-risk lesions. Once these lesions have been identified, the improvements in minimally invasive endoscopic therapies has meant that these patients can potentially be cured of early cancer and high-risk dysplastic lesions without the need for surgery, which still has a significant morbidity and mortality. The importance of reaching an accurate diagnosis of BE remains of paramount importance. More work is needed, however. The vast majority of those undergoing surveillance for their BE do not progress towards cancer and thus undergo a regular invasive procedure, which may impact on their psychological and physical well-being while incurring significant cost to the health service. New work that explores cheaper endoscopic or non-invasive ways to identify the at-risk individual provides exciting avenues for research. In future, the diagnosis and monitoring of patients with BE could move away from hospitals and into primary care.

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Acetic acid compared with i-scan imaging for detecting Barrett’s esophagus: a randomized, comparative trial

Cited by 40 publications

References 23 publications

Advanced Imaging in Barrett's Esophagus

Advanced Imaging in Barrett's Esophagus

Optimizing the diagnosis and therapy of Barrett’s esophagus

Monitoring the premalignant potential of Barrett's oesophagus'

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