Accurate Determination and Characterization of Gold Nanoparticles Based on Single Particle-Inductively Coupled Plasma-Mass Spectrometry

Ji, Chao; Wang, Jingru; Zhang, Jing-Qi

doi:10.1016/s1872-2040(20)60032-9

Cited by 4 publications

(6 citation statements)

References 21 publications

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“…The method provided accurate results in human serum samples with detection limits in the pM level. 298 ZnSe quantum dots were used for tagging antibodies in a sandwich-type magnetic immunoassay for determination of carcinoembryonic antigen in human serum with a detection limit of 6 pg mL -1 by monitoring 64 Zn. 299 The determination of cytokeratin fragment antigen 21-1, carbohydrate antigen, and carcinoembryonic antigen was carried out by a simultaneous sandwich-type immunoassay using antibody-immobilized magnetic beads and Au, Ag and ZnSe nanoparticle labels, respectively.…”

Section: Sp-icp-ms Based Immunoassay and Hybridization Methodsmentioning

confidence: 99%

“…The analysis of pristine nanoparticles is regarded as the least complex scenario, since there is no matrix in which they are contained. Engineered nanomaterials commonly produced at laboratories for research or industrial purposes, 61,[63][64][65][66][67][68][69][70][71][72]75,76 but also commercial suspensions, 60,62,73,74 have been considered in this section. Table 2 summarizes the applications of SP-ICP-MS to the analysis of such pristine nanoparticles.…”

Section: Scenario 0: Analysis Of Pristine Nanoparticlesmentioning

confidence: 99%

“…In any case, the main aim of the analysis is focused on the characterisation of the nanoparticles, although the effect on size of different factors (stability, 60 kinetics, 61 use of specific reagents 67,76 ) along their synthesis have also been studied by some authors. Pure nanoparticles of metallic Au, [63][64][65] Ag, 60,61,63 Pd and Ni, 68 as well as TiO 2 , 71 have been analysed by SP-ICP-MS. The nanoparticles were usually obtained by chemical synthesis, although they were also produced by milling.…”

Section: Scenario 0: Analysis Of Pristine Nanoparticlesmentioning

confidence: 99%

“…In relation to the analytical information delivered, size distributions and mean/median sizes were typically reported, although mass 61,68 and number concentration 64,68 were also considered when samples were originally presented as suspensions. In this scenario, characterisation was not only limited to sizing.…”

Section: Scenario 0: Analysis Of Pristine Nanoparticlesmentioning

confidence: 99%

“…In that way, the yttrium contained in nanotubes allowed their detection, 73,74 although the concentration was underestimated due to the difficulties of detecting nanotubes with low loads of yttrium. The characterisation of pristine nanoparticle by SP-ICP-MS has been complemented by electron microscopy techniques for size and shape characterisation 57,61,64,65,[68][69][70]73,74 and XRD 68,69,72,75 for confirmation of their nature through their crystalline structure.…”

Section: Scenario 0: Analysis Of Pristine Nanoparticlesmentioning

confidence: 99%

See 4 more Smart Citations

Analytical applications of single particle inductively coupled plasma mass spectrometry: a comprehensive and critical review

et al. 2021

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Section: Sp-icp-ms Based Immunoassay and Hybridization Methodsmentioning

confidence: 99%

Section: Scenario 0: Analysis Of Pristine Nanoparticlesmentioning

confidence: 99%

Section: Scenario 0: Analysis Of Pristine Nanoparticlesmentioning

confidence: 99%

Section: Scenario 0: Analysis Of Pristine Nanoparticlesmentioning

confidence: 99%

Section: Scenario 0: Analysis Of Pristine Nanoparticlesmentioning

confidence: 99%

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Analytical applications of single particle inductively coupled plasma mass spectrometry: a comprehensive and critical review

et al. 2021

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Nanomaterials‐Mediated Structural and Physiological Modulation of Blood Brain Barrier for Therapeutic Purposes

Ghouri

Saleem

Ren

et al. 2021

Adv Materials Inter

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Blood brain barrier (BBB) protects homeostasis and sensitive environment of brain from several toxic substances coming from the systemic circulation. This barrier along with those substances also prevents therapeutic chemicals to reach brain tissues for several brain diseases. BBB consists of a number of cell types and junctions that help maintain its intricate structure and physiology. To open BBB for therapeutic purposes, researchers are keen to explore the use of nanomaterials as therapeutic agents. Nanomaterials have unique physio‐chemical properties such as, increased surface area to mass ratio, superior adsorption capacity, and a wide variety of functionalization possibilities in contrast to bulk materials, making them sought‐after for research pertaining to brain delivery of therapeutic substances. Both organic and inorganic nanomaterials have been researched in this regard with numerous interesting functionalizations, and their toxicity and distribution profiles have been well assessed. Different pathways taken up by nanomaterials to cross BBB like adsorptive‐mediated transcytosis, inhibition of active efflux pumps, receptor‐mediated transport, and cell‐mediated endocytosis have also been investigated. This review summarizes the structural and physiological properties and the modulation techniques of BBB for delivery of adsorbed/functionalized nano delivery platforms and imaging nanomaterials across.

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Determination of nanoparticles concentration in solution based on Pickering emulsion destabilization analyses

Błaszczyk

Przybysz

2021

Appl Nanosci

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The dynamic development of nanotechnology research has contributed to the fact that various types of nanoparticles are increasingly used on a large scale both for medical and biological purposes, but above all in many industrial fields. Such a wide application of nanoparticles is often connected with the need to estimate their characteristic parameters, such as size, size distribution or concentration. Existing instruments are usually quite expensive and not always available. Therefore, other cheaper and simpler methods based on analytical techniques are sought. In this paper, we have proposed a method to estimate the concentration of nanoparticles in solutions based on destabilization analyses of Pickering emulsions produced with their use. The fact of mutual relationship between emulsion concentration, nanoparticle concentration and emulsion stability was used here. The study was carried out using silica nanoparticles. It was presented how to apply the method and what are its limitations. Moreover, an example of its application for the determination of nanoparticle concentration in an unknown sample, obtained after analysis of the permeability of membranes in diffusion chambers, has been presented. The method can become a useful alternative for the determination of nanoparticle concentration in solution in places where no specialized equipment is available.

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Accurate Determination and Characterization of Gold Nanoparticles Based on Single Particle-Inductively Coupled Plasma-Mass Spectrometry

Cited by 4 publications

References 21 publications

Analytical applications of single particle inductively coupled plasma mass spectrometry: a comprehensive and critical review

Analytical applications of single particle inductively coupled plasma mass spectrometry: a comprehensive and critical review

Nanomaterials‐Mediated Structural and Physiological Modulation of Blood Brain Barrier for Therapeutic Purposes

Determination of nanoparticles concentration in solution based on Pickering emulsion destabilization analyses

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