Accuracy of Combined Clinical-Mammographic-Cytologic Diagnosis of Dominant Breast Masses

Accuracy of Touch Imprint Cytology of Image-Directed Breast Core Needle Biopsies

“…Several studies have shown the advantage of a multimodality approach to breast cytology interpretation, with diagnostic accuracy close to that of histology. 2,5,11,17 One of the two cases of lactational change was called suspicious on TI cytology. On subsequent review, the TI cytology was noted to be highly cellular, with several intact single cells, many not showing the finely vacuolated cytoplasm typical of a One case of lactational change was suspicious on TI cytology (Figure 3).…”

Value of Fine Needle Aspiration in the Diagnosis of Breast Lesions

“…[2][3][4][5][6]8,9,11,13,14,16,17,19,22,25,26,29,31,33,35,38,40,[43][44][45] The clinical utility of a diagnostic procedure depends on the context in which it is used. A screening test should have as high a sensitivity rate as possible, and a lower specificity rate is acceptable in this setting.…”

“…The correlation of results was analyzed by a decision-analysis approach to determine the utility or relative desirability of aspiration cytology. The following values concerning diagnostic accuracy were calculated in the present study and in 25 other reports from the literature [2][3][4][5][6]8,9,11,13,14,16,17,19,22,25,26,29,31,33,35,38,40,[43][44][45] : (1) sensitivity, the probability of a positive FNA result given that the patient has carcinoma; (2) specificity, the probability of a negative FNA result given that the patient has a benign lesion; (3) positive predictive value, the probability of having carcinoma when the results of FNA are positive; (4) negative predictive value, the probability that a tumor is benign when the results of FNA are negative; (5) FPF, the fraction of all benign lesions reported as positive by FNA; and (6) FNF, the fraction of all carcinomas reported as negative on FNA.…”

Accurate Evaluation of Palpable Breast Masses by the Triple Test Score

“…The TTS was correlated with subsequent histopathologic examination results, except in 112 lesions with benign concordant TT results (TTS = 3), for which clinicians and patients chose close follow-up based on multiple earlier studies. [1][2][3][4][5][6][7] Accuracy rates for the TTS were then determined from standard formulas, as in previous reports Multiple previous studies have shown that a mass with a concordant benign TT result can be safely followed up without open biopsy. [1][2][3][4][5][6][7] This is especially helpful in evaluating low-risk masses or multiple masses in a young patient with, for example, fibrocystic breast changes.…”

“…[1][2][3][4][5][6] In 1995, our group performed a prospective, internally controlled trial wherein every lesion was evaluated by both TT and subsequent open biopsy. 7 We found that the TT for palpable breast masses yields 100% diagnostic accuracy when all 3 elements are concordant (all benign or all malignant).…”