Value of Fine Needle Aspiration in the Diagnosis of Breast Lesions

Collaço, Luiz Martins; Lima, Rubens Silveira de; Werner, Betina; Torres, Luíz Fernando Bleggi

doi:10.1159/000331150

Cited by 36 publications

(26 citation statements)

References 25 publications

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“…This value has varied tremendously in other studies, ranging from 0.7-47%. [12][13][14]17,21,31,32 The wide variation in the numbers of inadequate specimens in different series may depend on the criteria for calling a specimen inadequate. Adequacy guidelines with respect to the number of epithelial cells required have been published, with fewer than six epithelial cell clusters considered inadequate.…”

Section: Resultsmentioning

confidence: 99%

Effectiveness of fine‐needle aspiration cytology of breast: Analysis of 2,375 cases from northern Thailand

Chaiwun

Settakorn

Ya-In

et al. 2002

Diagnostic Cytopathology

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At the Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Thailand, 2,375 cases of breast lesions were sampled by fine-needle aspiration (FNA) from 1994-1999. Cytologic diagnoses were: benign (48%), suspicious for malignancy (5%), malignant (15%), and unsatisfactory (32%). Comparison with histology was possible in 721 cases. The diagnoses obtained by FNA showed a sensitivity of 84.4%, specificity of 99.5%, positive predictive value of 99.8%, negative predictive value of 84.3%, false-negative rate of 16.7%, false-positive rate of 0.5%, and overall diagnostic accuracy of 91.3%. We conclude that, in experienced hands, FNA of breast masses is reliable for diagnosis. Assessment of samples at the time of aspiration can reduce the number of inadequate specimens to near zero. Correlation of FNA results with clinical and radiologic findings can identify false-negatives and false-positives, ensuring optimal patient management. Many centers now recommend needle core biopsy instead of FNA. For regions such as ours, the added cost of this test would make it unavailable to many patients, which could delay a diagnosis of breast cancer. We advocate keeping FNA as a first-line diagnostic procedure, at least in areas under economic restrictions, in order to maximize the availability of health care to women with breast disease.

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Section: Resultsmentioning

confidence: 99%

Effectiveness of fine‐needle aspiration cytology of breast: Analysis of 2,375 cases from northern Thailand

Chaiwun

Settakorn

Ya-In

et al. 2002

Diagnostic Cytopathology

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“…The reported sensitivity and specificity of breast FNA ranges from 94% to 100% and 98% to 100%, respectively. [1][2][3] It is known that there are some benign proliferative breast lesions that can exhibit cytologic features similar to those of low-grade or sparsely cellular carcinomas. 4 Many authorities have recognized this limitation of breast cytopathology and have advocated the use of a categorical or probabilistic approach for reporting breast FNA to limit false positive and false negative di-agnoses.…”

mentioning

confidence: 99%

Application of the Probabilistic Approach to Reporting Breast Fine Needle Aspiration in Males

MacIntosh¹,

Merrimen²,

Barnes³

2008

Acta Cytologica

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“…Muhamed et al [26] 90.6 100 100 99 -Rubin et al [27] 87 100 100 89 -Ishikawa et al [28] 86.3 98.2 97.9 --Collaco et al [29] 92. …”

Section: Resultsmentioning

confidence: 99%

Cytological and Histopathological Correlation of Breast Lump: A 3 Year Study at Tertiary Care Center

Chauhan

Sarvaiya

2017

APALM

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Background: The fine needle aspiration cytology (FNAC) is an OPD procedure that is easy to perform, accurate, reproducible and cheap. Fine needle aspiration is a part of triple test to diagnose the breast lump. However a definitive conclusion should always be reached through histopathological examination Aim:The aim of our study is to correlate cytological diagnosis with histopathological diagnosis, to know clonicomorphologic spectrum of breast lump, and to figure out sensitivity, specificity, positive predictive value, negative predictive value and efficiency of FNAC. Methods:Total 244 cases who were subjected to FNAC and then subsequent biopsy was sent in each case were taken into consideration for analysis from tertiary care center in north Gujarat from February 2014 to January 2017 for 3 years.Results: In our study,4 were males and 240 were females(1.64% and 98.36% respectively). Maximum cases of breast lump were in the 21-30 years age group. Out of total 244 cases 154(63.11%) were benign, 50(20.49%) cases were malignant, 08 (3.27%) were suspicious for malignancy and 32(13.11%) were other nonneoplastic. Out of total 244 cases, 241 were consistent on histopathology and 3 were inconsistent. Our study have Sensitivity, Specificity, Positive predictive value, Negative predictive value, and Efficiency to be 98.24%, 98.93%, 96.55%, 99.46% and 98.77% respectively. Conclusion:FNAC helps the surgeon on further accurate management of lump as it is sensitive and specific. FNAC results should be correlated with clinical findings and radiological investigations. Inconclusive results and on FNAC should always be confirmed with biopsy.

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Value of Fine Needle Aspiration in the Diagnosis of Breast Lesions

Cited by 36 publications

References 25 publications

Effectiveness of fine‐needle aspiration cytology of breast: Analysis of 2,375 cases from northern Thailand

Effectiveness of fine‐needle aspiration cytology of breast: Analysis of 2,375 cases from northern Thailand

Application of the Probabilistic Approach to Reporting Breast Fine Needle Aspiration in Males

Cytological and Histopathological Correlation of Breast Lump: A 3 Year Study at Tertiary Care Center

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