Accelerated schedule of hepatitis B vaccination in high‐risk youth

Se, Wilkinson; Morath, M; Dl, Bennett; Ma, Burgess; Isaacs, David

doi:10.1111/j.1440-1754.1996.tb01544.x

Cited by 17 publications

(12 citation statements)

References 13 publications

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“…Various studies concluded that a rapid vaccination scheme gave similar results with a traditional vaccination scheme, and anti-HBs response was maintained for at least 1 year [19, 20]. In our study, all cases administered a rapid vaccination scheme had developed a protective anti-HBs response at the end of month 1, while only five subjects in the group administered a traditional vaccination scheme had developed a protective anti-HBs response at the end of month 1.…”

Section: Discussionsupporting

confidence: 62%

Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital Tests

Tosun¹,

Yücetürk²,

Dönmez³

et al. 2012

Clinical and Developmental Immunology

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Background. The aim of this study was to monitor the cases identified as hepatitis B carriers during premarital tests, to vaccinate their prospective spouses with a rapid vaccination scheme, and to compare the anti-HBs responses with the traditional vaccination scheme. Methods. Blood samples of 1250 couple spouses were tested for HBsAg and anti-HBs. HBsAg positive cases' fiancées which were found HBV negative were administered a rapid three-dose vaccination scheme on days 0, 7, and 21. Forty controls with similar age and gender were also were administered three doses of the same vaccine. Results. Out of 1250 cases (625 couples), 46 (3.6%) were HBsAg positive, and 40 of them aged between 18 and 39 were admitted to the rapid vaccination program. Conclusion. Upon determination of HBsAg positivity in premarital tests, a rapid vaccination program provides early protection, but the 6th and 12th month vaccinations are also required. Anti-HBs response should be monitored.

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Section: Discussionsupporting

confidence: 62%

Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital Tests

Tosun¹,

Yücetürk²,

Dönmez³

et al. 2012

Clinical and Developmental Immunology

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“…Based on this finding, the authors 'strongly recommend against the 0-1-2 schedule for drug user patients'. Although most, but not all (Wilkinson et al 1996), studies indicate that the longer the interval between the second and third vaccine doses, the greater the seroresponse, the differences in seroresponse (solely on account of differences in vaccine schedule) determined by the authors are much higher than the relatively modest differences determined by fellow workers. For example, a New South Wales study of 455 inmates vaccinated using the 0-1-2 vaccination schedule and a 20 mg/dose vaccine showed a seroresponse rate of 85% (Awofeso 2002) compared with 89% among healthy adult volunteers using the same schedule (Smith- Kline Beecham 1999).…”

Section: Managerial Considerations In Implementing Hepatitis B Vaccinmentioning

confidence: 79%

Sports involvement can be both formal and informal at the same time: a comment on peretti‐watel et al.

2002

Addiction

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Sir-Peretti-Watel et al .'s paper (Peretti-Watel et al. 2002) was quite a surprise for the investigators of the European School Survey on Alcohol and other Drugs (ESPAD) 1999, who introduced the additional sport variables (Choquet & Arvers 2002). The main focus of this letter is a complementary analysis. Peretti-Watel et al. (2002) concluded that 'results stress the need to control for age and gender'. Yet since sport practice decreases by age while substance use increases, it appeared more reasonable to perform a separate analysis on each age group rather than adjustments on age. The authors also mentioned that 'the relationship between drug use and sport activity depends on the type of sport'. Since the average number of sports practised was about 3.4 (CI 95% 3.3-3.5) in boys and 2.5 (CI 95% 2.4-2.6) in girls, analysis according to the type of sport should be performed cautiously. But the authors did not mention participation in sport competitions, one of the sport questions added to the ESPAD questionnaire. We propose a complementary analysis of the ESPAD 1999 sample described by Peretti-Watel et al. (2002). We analysed the age group 16-18 years (n = 5983; 96.4% replied to the questions concerning sport activities), which is the most representative of the scholar population (the under-16s and over-18s may be following academic programmes not selected in the sample). We performed logistic regressions separately by gender and by each substance, considering not only alcohol, tobacco and cannabis (see ESPAD 1999 criteria, Hibell et al. 2000) but also illicit drugs other than cannabis (7.9%). As explanatory variables, we took into account the exact age, the duration of sports practice

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“…In young drug-using populations, such barriers include access to health services, 17 cost of vaccine, 9 vaccination setting, 18 and duration of the vaccination course. 19 Thus, the removal of structural barriers in this project through proactive recruiting of at-risk youth (including non-IDUs), removing vaccination costs, shortening the time course of the vaccination schedule, and providing follow-up and reminder services, clearly assisted in the high level of completed vaccinations. In addition, the removal of attitudinal barriers, such…”

Section: Discussionmentioning

confidence: 99%

An accelerated hepatitis B vaccination schedule for young drug users

Rogers¹,

Lubman

2005

Australian and New Zealand Journal of Public Health

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Objective: Jo determine completion rates for an accelerated hepatitis B vaccine (HBV) program among a population of young drug users. Design: Between January 2001 and May 2002, a three‐dose course of HBV vaccine (0, 7 and 21 days) was offered free to all drug users (aged 22 years or younger) accessing two outreach sites of a youth‐focused support and drug treatment service in metropolitan Melbourne, Australia. Clients were offered vaccination in any safe environment of their choice. An audit was conducted on the health records of participating clients. Main outcome measures: Number of completed vaccinations; settings in which vaccinations were completed. Results: Ninety young people accepted vaccination, with 71% completing the full course. The majority preferred to receive vaccination at drug treatment outreach sites (53%). Conclusions: An accelerated vaccination schedule appears acceptable to young drug users, suggesting that vaccination programs can be successful when barriers to immunisation are appropriately identified and addressed.

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Accelerated schedule of hepatitis B vaccination in high‐risk youth

Abstract: High-risk youth can be immunized against hepatitis B successfully using an accelerated schedule, but compliance is difficult.

Cited by 17 publications

References 13 publications

Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital Tests

Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital Tests

Sports involvement can be both formal and informal at the same time: a comment on peretti‐watel et al.

An accelerated hepatitis B vaccination schedule for young drug users

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