Acacia Gum Hydrogels Embedding the In Situ Prepared Silver Nanoparticles; Synthesis, Characterization, and Catalytic Application

Ihsan, Junaid; Ullah, Shafqat; Khan, Muhammad Aslam; Khan, Aisha Saleem; Muhammad, Saz; Ahmad, Nisar; Haleem, Abdul; Shah, Luqman Ali; Saeed, Shaukat; Siddiq, Muhammad

doi:10.1007/s10562-020-03380-z

Cited by 16 publications

(9 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…loss was observed in first degradation temperature range of 92–236°C against cross‐linked GA. The preceding weight loss might be due to shows the elimination of associated water molecules (Ihsan et al, 2020). The second, third and fourth degradation steps for pristine GA microgels give upto 11%, 45% and 74% weight losses over the temperatures range of 200–250°C, 250–300°C, and 310–44°C, respectively.…”

Section: Resultsmentioning

confidence: 99%

Synthesis, characterization, and biological screening of metal nanoparticles loaded gum acacia microgels

Ihsan

Ullah

Khan

et al. 2021

Microscopy Res & Technique

Self Cite

View full text Add to dashboard Cite

We report novel gum acacia (GA) based microgels composites for multifunctional biomedical application. High yield of spherical GA microgels particles within 5-50 μm size range was obtained via crosslinking the polymer in the reverse micelles of surfactantsodium bis (2-ethylhexyl) sulfosuccinate (NBSS) in gasoline medium. The prepared microgels were then utilized for in situ silver (Ag) and cobalt (Co) nanoparticles (NPs) synthesis to subsequently produce GNAg and GNCo nanocomposite microgels, respectively. Ag and Co NPs of particle of almost less than 40 nm sizes were homogenously distributed over the matrices of the prepared microgels, and therefore, negligible agglomeration effect was observed. Pristine GA microgels, and the nanocomposite microgels were thoroughly characterized through FTIR, DSC, TGA, XRD, SEM, EDS, and TEM. The well-characterized pristine GA microgels and the nanocomposite microgels were then subjected to multiple in vitro bioassays including antioxidant, antidiabetic, and antimicrobial activities as well as biocompatibility investigation. Our results demonstrate that the prepared nanocomposites in particular GNAg microgels exhibited excellent biomedical properties as compared to pristine GA microgels. Among the prepared samples, GNAg nanocomposites were highly active against Fusarium oxysporum and Aspergillus niger that show 47.73% ± 0.25 inhibition and 32.3% ± 2.0 with IC-50 of 220 μg ml −1 and 343 μg ml −1 , respectively. Moderate antidiabetic activity was also observed for GNAg nanocomposites with considerable inhibition of 15.34% ± 0.20 and 14.7% ± 0.44 for both α-glucosidase and α-amylase, respectively. Moreover, excellent antioxidant properties were found for both the GNAg and GNCo nanocomposites as compared to pristine GA microgels. A remarkable biocompatible nature of the nanocomposites in particular GNAg makes the novel GA composites, to be exploited for diverse biomedical applications.

show abstract

Section: Resultsmentioning

confidence: 99%

Synthesis, characterization, and biological screening of metal nanoparticles loaded gum acacia microgels

Ihsan

Ullah

Khan

et al. 2021

Microscopy Res & Technique

Self Cite

View full text Add to dashboard Cite

show abstract

“…After a 48-hour incubation, the Zone of Inhibition was evaluated using the positive and negative controls, clotrimazole and DMSO, respectively. A Vernier calliper was used to calculate the zone of inhibition [19].2.4.2. Biocompatibility StudyUsing freshly collected human blood, the haemolytic activity test was performed to evaluate the interaction between red blood cells and NPs and the toxicity of the latter.…”

Section: Characterization Of Nanoparticlesmentioning

confidence: 99%

Wild Mushroom (Ganoderma multipileum) as Biosource for Zinc oxide Nanoparticles: From Synthesis to Enhance Biological Applications

Kamal

Batool

Saba

et al. 2023

Preprint

View full text Add to dashboard Cite

In the current investigation, a macrofungus was collected from Quaid-i-Azam University Islamabad. The collected fungus was identified as Ganoderma multipileum, and further exploited for the synthesis of nanoparticles using zinc metals. Chemical and morphological characterization of synthetized nanoparticles was through Fourier Transfer InfraRed spectroscopy analysis (FTIR), X-ray diffraction analysis (XRD), Energy dispersive X-ray analysis (EDX), Scanning Electron Microscopy analysis (SEM) and UV-Vis spectrum showed a broad absorption between 350 and 380 nm, which indicates the synthesis of ZnO NPs. ZnONPs have been used in a variety of biomedical studies including such as biocompatibility, antifungal, antileishmanial, and antibacterial studies. abilities, antifungal, antileishmanial, and antibacterial studies. The ZnO nanoparticles showed a strong antibacterial effect against gram-positive (Klesbsilla pneumonia and Staphylococcus aureus) and gram-negative (Eschericia coli and Pseudomonas aeruginosa) bacteria. Furthermore, the ZnO nanoparticles also showed a high antifungal effect against different fungus. The current study concludes that Ganoderma multipileum works as a novel and eco-friendly source for the synthesis of ZnO NPs with prominent biological application that can be further applied in different fields.

show abstract

“…To coup with this issue, various stabilizing methods, such as, dendrimers, polymeric gels, and some natural entities are incorporated to protect NPs active surface for enhanced efficacy. Natural entities used for NPs reduction purpose are various plants, fungi and bacteria to carry out biosynthesis of NPs under green nano-technological protocols [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Hierarchical plant extracts in silver nanoparticles preparation: Minuscular survey to achieve enhanced bioactivities

Habib,

Bibi,

Qayyum

et al. 2024

Heliyon

Self Cite

View full text Add to dashboard Cite

Acacia Gum Hydrogels Embedding the In Situ Prepared Silver Nanoparticles; Synthesis, Characterization, and Catalytic Application

Cited by 16 publications

References 57 publications

Synthesis, characterization, and biological screening of metal nanoparticles loaded gum acacia microgels

Synthesis, characterization, and biological screening of metal nanoparticles loaded gum acacia microgels

Wild Mushroom (Ganoderma multipileum) as Biosource for Zinc oxide Nanoparticles: From Synthesis to Enhance Biological Applications

Hierarchical plant extracts in silver nanoparticles preparation: Minuscular survey to achieve enhanced bioactivities

Contact Info

Product

Resources

About