1999
DOI: 10.1093/ndt/14.1.129
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Abysmal prognosis of patients with type 2 diabetes entering dialysis

Abstract: Our observational study illustrates the high burden of cardiovascular diseases contrasting with sub-optimal cardiovascular therapeutic interventions in type II diabetes patients entering dialysis. Factors aggravating renal failure were mainly iatrogenic, and therefore largely avoidable. Late referral generally implied a poor clinical condition at the start of dialysis.

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Cited by 105 publications
(47 citation statements)
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“…After 211 days, 32% of diabetic patients were deceased secondary to CVD. In this study the authors also determined that early referral of patients to nephrologists could improve prognosis (20). Our findings were also consistent with this study.…”
Section: Dıscussıonsupporting
confidence: 91%
“…After 211 days, 32% of diabetic patients were deceased secondary to CVD. In this study the authors also determined that early referral of patients to nephrologists could improve prognosis (20). Our findings were also consistent with this study.…”
Section: Dıscussıonsupporting
confidence: 91%
“…The reason that we were not able to show an association between ESRF and Pro12Ala in our patients with type 2 diabetes might be related to the fact that ESRF is a more complex phenotype that is determined by a plethora of different pathophysiological as well as genetic factors. However, patients with type 2 diabetes have an excessive cardiovascular risk, leading to a dramatically reduced survival before ESRF develops (6,19), therefore introducing a bias toward low ESRF rates that hampers the unraveling of the underlying genetic risk factors. In the development of diabetic nephropathy, morphologic changes such as thickening of the glomerular basement membrane, glomerular hypertrophy, mesangial expansion, and modest expansion of the tubulointerstitium play a role.…”
Section: Discussionmentioning
confidence: 99%
“…Aunque al comparar la prevalencia de factores de riesgo entre diabéticos y no diabéticos solo se observaron diferencias importantes en cuanto al ITB e IMC alterados, varios estudios han demostrado el mayor riesgo de complicaciones cardiovasculares en los pacientes diabéticos y los beneficios de la intervención integral [22][23][24] , en este sentido, adicional al control metabólico, acciones como la medición del para los pacientes y eficiencias para el sistema de salud. Estudios posteriores evaluarán el modelo en términos de desenlaces clínicos, costos y calidad de vida de los pacientes.…”
Section: Tablaunclassified