“…A major theoretical advantage of beta-microprobes includes their high temporal resolution to capture the peak of the time-activity curve. However, during time-activity curve pre-processing and in accordance with literature (Pain et al, 2002 ; Zimmer et al, 2002 ; Ginovart et al, 2004 ; Moulin-Sallanon et al, 2005 ; Märk et al, 2013 ; Balasse et al, 2014 ), we were forced to resample the curves to larger time frames due to high signal noise associated with beta-microprobe recordings. We resampled the data to μPET frames: 2 × 10 s, 3 × 20 s, 3 × 30 s, 3 × 60 s, 3 × 150 s, 9 × 300 s. In this way, the beneficial theoretical temporal resolution of 1 s was lost.…”