A Water-Soluble Fluorescent Probe for the Selective Sensing of Ag+ and its Application in Imaging of Living Cells and Nematodes

Ti3C2Tx MXene Nanosheet-Based Probe for Ion Fluorescence and Visual Detection of Ag+ in Aqueous Solution and Living Cells

“…A series of detection methods have been developed to detect silver ions, such as atomic absorption spectroscopy, inductively coupled plasma–mass spectroscopy, and ion-selective electrodes. , However, these methods mentioned above all require expensive equipment or complex technology. − On this basis, fluorescent probes have become a popular method due to their high sensitivity, rapidity, simple operation, common instruments, and suitability for biological systems. − In the past years, some fluorescent probes for detecting silver ions have been developed, but the following defects are still not solved. − First, some currently reported methods utilize the “silent ion” of silver ions to quench their fluorescence, which is not conducive to high signal output. , Second, the proposed probes only show moderate fluorescence changes, small response range to silver ion concentration, so the sensitivity of these probes is usually not enough to detect low concentrations of silver ions in water samples. , Finally, the probes reported in the literature are difficult to distinguish Ag + from other metal ions (such as Au 3+ ). , Therefore, it is an urgent need to develop a novel fluorescent probe with high sensitivity and selectivity in real samples. − …”