A Tropical Lichen Planus-Like Disease

Lichen planus: review and update on pathogenesis

“…The oeeurrenee of lesions having the elinieal and histopathological features of LP, but apparently indueed by drugs, has been reeognised for sotne time but the importance was emphasized by the large nutnber of eases of LP that appeared in service personnel receiving antimalarials in World War II. These quinaerine-indueed "lichenoid" lesions were widely reported (208,209,210,211,212,213), A vast range of drugs have been implicated in the aetitilogy of lichenoid lesions that may involve the skin and/tir mucous membranes, but most patients with LP are not using any of these medications (9). Stime drugs tiften cause mucosal lichenoid lesitins; quinacrine ftir example caused oral lesions in 47' y<> of those affected with LP (211).…”

Lichen Planus in Subtropical Countries

“…Summary of Case.-In an 18 year old patient of dark complexion, whose parents had immigrated from Iran, lesions developed on the ex¬ posed parts of the body. These lesions appeared with seasonal fluctuation during the course of seven years.…”

Tropical Lichen Planus Syndrome

“…The evolution of the clinical picture followed closely that described by Bagby (1945). Three representative case histories are given.…”

“…The condition was briefly referred to by Myers (1944) in the course of a review of skin diseases affecting Australian troops in New Guinea. A detailed account of the findings in some American cases has been given by Bagby (1945). The aetiology is not definitely established, but there is substantial evidence that the disease has some relation to the use of mepacrine as a malaria suppressive.…”