A Technique for Resection of Invasive Tumors Involving the Trigone Area of the Bladder in Dogs: Preliminary Results in Two Dogs

Abstract

Objective-To describe a surgical technique for resection of the entire bladder neck, including the trigone and proximal urethra in dogs with invasive tumors causing life-threatening urinary tract obstruction. Study Design-Clinical case reports. Animals-Dogs (n ¼ 2) with bladder tumors. Methods-Circumferential excision of the bladder neck and proximal urethra with preservation of the neurovascular pedicles was performed to remove a rhabdomyosarcoma (dog 1) and a transitional cell carcinoma (dog 2) involving the trigone and bladder neck that were causing urinary tract obstruction. Reconstruction of the bladder and proximal urethra included bilateral ureteroneocystostomy. Adjuvant chemotherapy was administered postoperatively to both dogs. Results-Postoperatively, dogs 1 and 2 were continent after 7 and 17 days, respectively, and regained normal urinary function after resolution of a transient pollakiuria. Dog 1 had no evidence of local or regional recurrence; however, a large solitary pulmonary metastatic lesion was diagnosed 8 months later. The dog was euthanatized despite a lack of clinical signs. Dog 2 had at least 1 metastatic lesion in the abdominal wall 6 months later and was euthanatized at 580 days because of renal failure. Conclusion-En-bloc removal of the bladder neck and proximal urethra with preservation of the dorsal vascular and nervous pedicles, although a technically challenging procedure, can be performed without associated urinary incontinence or bladder wall necrosis. Clinical Relevance-In dogs with invasive bladder tumors causing life-threatening urinary tract obstruction, resection of the bladder neck and proximal urethra should be considered as a promising surgical alternative to urinary diversion. r

Subcutaneous embryonal rhabdomyosarcoma in a dog: cytologic, immunocytochemical, histologic, and ultrastructural features

“…Embryonal rhabdomyosarcoma is further classified into 2 subtypes: round cell type, composed of round to polygonal cells (rhabdomyoblasts) admixed with smaller cells, and myotubular type, which is similar to the spindle cell type described in people and composed of cells resembling primitive myocytes termed myotubes 3 . Embryonal myotubular rhabdomyosarcoma is the most common canine variant, with botryoid rhabdomyosarcoma most frequently found in the urinary bladder, whereas the round cell type usually arises in other locations 3–5,8–16 . Botryoid rhabdomyosarcoma of the urinary bladder forms typical grape‐like or “botryoid” polypoid masses 3 .…”

Localization of peripheral autonomic neurons innervating the boar urinary bladder trigone and neurochemical features of the sympathetic component

“…Therefore, it plays a vital role in maintaining continence and aiding micturition. Moreover, the UBT represents an elective site for cancer proliferation, in both veterinary 9,10 and human 11 medicine. Hence, we believe that the knowledge of UBT nervous pathways is essential for a better insight into the control of bladder storage and voiding in health and disease.…”

Outcome of urethral stent placement for management of urethral obstruction secondary to transitional cell carcinoma in dogs: 19 cases (2007–2010)

“…[7][8][9] A novel approach that uses ultrasound-guided cystoscopic laser ablation of urethral TCC has also been reported; however, this technique is also technically challenging, requires repeated procedures and lengthy hospital stays, and is associated with considerable cost. [7][8][9] A novel approach that uses ultrasound-guided cystoscopic laser ablation of urethral TCC has also been reported; however, this technique is also technically challenging, requires repeated procedures and lengthy hospital stays, and is associated with considerable cost.…”