A systematic review and meta‐analysis of the effect of Vitamin D‐fortified food on glycemic indices

Emadzadeh, Maryam; Sahebi, Reza; Khedmatgozar, Hamed; Sadeghi, Ramin; Farjami, Mahsa; Sharifan, Payam; Ravanshad, Yalda; Ferns, Gordon A.; Ghayour‐Mobarhan, Majid

doi:10.1002/biof.1632

Cited by 10 publications

(2 citation statements)

References 37 publications

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“…Additionally, there was no signi cant relationship reported in our research between hemoglobin A1C and vitamin D levels. Similarly, a recent meta-analysis revealed that eating foods higher in vitamin D was linked to a lower HbA1c; however, the difference was not statistically signi cant (55). Nonetheless, some research ndings indicate that vitamin D signi cantly lowers HbA1c in those with prediabetes or diabetes (56-58).…”

Section: Discussionmentioning

confidence: 99%

Association of serum 25-hydroxy vitamin D status with cardiometabolic risk factors and total and regional obesity in southern Iran: Evidence from the PoCOsteo study

Nejabat,

Emamat,

Afrashteh

et al. 2023

Preprint

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Cardiometabolic risk factors increase the chance of developing cardiovascular disease (CVD) and type 2 diabetes. Most CVD risk factors are influenced by total and regional obesity. A higher risk of developing CVD may be linked to vitamin D deficiency, which is more prevalent in the older population. With the goal of evaluating the association between vitamin D and cardiometabolic risk factors and total and regional obesity in older adults, this research included 25 (OH) vitamin D levels and biochemical markers associated with cardiometabolic diseases, as well as total and regional adiposity, which was measured by DXA. A total of 1991 older participants in the PoCOsteo study were included. Overall, 38.6% of participants had vitamin D deficiency. After adjusting for confounders, the results of multiple linear regression suggested an inverse association between vitamin D and body mass index (P = 0.040), waist circumference (P = 0.001), total fat (P = 0.020), android fat (P = 0.001), visceral fat (P < 0.001), subcutaneous fat (P = 0.011), trunk fat (P = 0.006), arm fat (P = 0.037), diastolic blood pressure (P = 0.003), total cholesterol (P < 0.001), LDL-cholesterol (P < 0.001), triglycerides (P < 0.001), and fasting glucose (P < 0.001). Additionally, higher vitamin D levels decreased the risk of dyslipidemia by 2%. Our results showed a significant association between serum vitamin D and a number of cardiometabolic risk factors, including total and regional obesity.

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Section: Discussionmentioning

confidence: 99%

Association of serum 25-hydroxy vitamin D status with cardiometabolic risk factors and total and regional obesity in southern Iran: Evidence from the PoCOsteo study

Nejabat,

Emamat,

Afrashteh

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Vitamin D deficiency has become a major health challenge among many countries in the 21 st century and is associated with an increased risk of several serious chronic diseases. The health benefits of this fat-soluble vitamin have been reported to include the prevention of chronic diseases, including those of the musculoskeletal system and bone metabolism ( 1 – 3 ).…”

Section: Introductionmentioning

confidence: 99%

The Effects of Vitamin D Fortified Products on Bone Bi-omarkers: A Systematic Review and Meta-Analysis

Emadzadeh¹,

Mehdizadeh²,

Sharifan³

et al. 2022

ijph

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Background: Vitamin D plays an essential role in the regulation of bone metabolism. The current meta-analysis aimed to assess the effectiveness of vitamin D fortification on special bone biomarkers. Methods: Five main databases (PubMed/Medline, ISI Web of Knowledge, Science Direct, Scopus, Cochrane Library as well as Science Direct, and Scopus) were considered for this systematic review, until Jan 2020. All randomized controlled trials were included to evaluate the probable relationship between consumption of vitamin D fortification products and bone biomarkers profile in this review. Results: Among serum bone biomarkers (osteocalcin and telopeptides of type-1 collagen) investigated, only the level of telopeptides of type-1 collagen significantly decreased after fortification of vitamin D in the intervention group. A significant increase in vitamin D was seen in those older than 18 yr old, while the increase in younger children was not statistically significant between intervention and control groups. Conclusion: Vitamin D fortification was not associated with a significant improvement in bone mass density (BMD), while it resulted in decreased PTH levels. Vitamin D fortified foods have some benefits on bone health due to increase in the level of vitamin D and IGF-1; and decreasing PTH and CTx levels.

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Marine‐Derived Sources of Nutritional Vitamins

Dashputre¹,

Sable²,

Sawant

et al. 2023

Vitamins as Nutraceuticals

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A systematic review and meta‐analysis of the effect of Vitamin D‐fortified food on glycemic indices

Cited by 10 publications

References 37 publications

Association of serum 25-hydroxy vitamin D status with cardiometabolic risk factors and total and regional obesity in southern Iran: Evidence from the PoCOsteo study

Association of serum 25-hydroxy vitamin D status with cardiometabolic risk factors and total and regional obesity in southern Iran: Evidence from the PoCOsteo study

The Effects of Vitamin D Fortified Products on Bone Bi-omarkers: A Systematic Review and Meta-Analysis

Marine‐Derived Sources of Nutritional Vitamins

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