A Survey of Australian Solanum Plants for Potentially Useful Sources of Solasodine

Bradley, V. L.; Collins, DJ; Crabbe, PG; Eastwood, FW; Irvine, MC; Swan, JM; Symon, DE

doi:10.1071/bt9780723

Cited by 29 publications

(12 citation statements)

References 22 publications

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“…Several glycosides are reported to occur; the most common are solasonine and solamargine. Varying responses for solasodine, solanidine, solasodiene, tomatidine, demissidine and other compounds have been found using methyl-orange (Bradley et al 1978). Solasodiene is formed by dehydration of solasodine under conditions of acid hydrolysis.…”

Section: Introductionmentioning

confidence: 99%

Production of steroidal alkaloids by hairy roots of Solanum aviculare and the effect of gibberellic acid

Subroto

Doran

1994

Plant Cell Tiss Organ Cult

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Cultures of Solanum aviculare hairy roots were established after transformation with Agrobacterium rhizogenes A4. High levels of steroidal alkaloids measured as solasodine equivalents were produced in shake-flasks and bioreactor, even though relatively low concentrations are found in roots in vivo. In shake flasks the maximum alkaloid yield was 32 mg g-1 dry weight; in a 3-1 air-driven bioreactor the yield was 29 mg g-1. These yields represent a 5-fold increase over previous reports for in vitro production, and are comparable with levels found in the aerial parts of intact S. aviculare plants. Production of steroidal alkaloids was growth-associated. High sugar levels at stationary phase and insensitivity to increased levels of medium components suggest that root cultures were limited by oxygen mass-transfer. In Petri-dish culture with and without exogenous gibberellic acid, root length and number of root tips increased exponentially; growth proceeded with a constant length per root tip of about 35 mm. Addition of gibberellic acid enhanced growth but reduced the specific steroidal-alkaloid level. Taking into account both growth and alkaloid yield, accumulation of steroidal alkaloids was improved by about 40% at gibberellic-acid concentrations of 10 and 100 ~tg 1 -l

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Section: Introductionmentioning

confidence: 99%

Production of steroidal alkaloids by hairy roots of Solanum aviculare and the effect of gibberellic acid

Subroto

Doran

1994

Plant Cell Tiss Organ Cult

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“…One of the alternatives under investigation has been production of the steroidal alkaloid, solasodine -a nitrogen analogue of diosgenin -from various plant species (Mann 1978). The 7 presently recognised species of the subgenus Archaesolanum have been of particular interest, as they all contain solasodine glycosides in varying amounts (Bradley et al 1978;Briggs & Cambie 1958;Lewis & Liljegren 1970). Reported and unreported studies indicate that Solanum aviculare Forst.…”

Section: Introductionmentioning

confidence: 99%

Genotype-environment interaction in poroporo (Solanum aviculare)

Beatson¹,

Rohrbach²

1985

New Zealand Journal of Agricultural Research

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Three small genotype X environment experiments were conducted on a random sample of poroporo (Solanum aviculare) lines taken from natural habitats, to evaluate their performance under commercial conditions. Considerable genotype X environment interaction was noted for the 3 characters measured: dry matter yield, solasodine yield, and solasodine percentage. Because of the large genotype X environment interaction observed in these trials, care should be taken in any interpretation of single location and single season results.

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“…Maori, indigenous people of New Zealand, used the leaf of S. laciniatum to form poultices to treat ulcers. 16 It is an important source of solasodine 17 and it is very plausible it would have been investigated for medicinal purposes by Aborigines in this region.…”

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confidence: 99%

Antimicrobial Activity of Extracts from Native Plants of Temperate Australia

Wigmore¹,

Naiker²,

Bean³

2016

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Introduction: Significant effort has been invested in looking at the antimicrobial activity of plant extracts from tropical regions of Australia, with less interest in those from more temperate environments. We sought to redress this imbalance by examining antimicrobial activities of extracts from native plants of Victoria. Methods: Sixteen plant samples were obtained around the Ballarat region of Victoria. Plant material was desiccated, ground and extracted with methanol at room temperature. Methanol extracts were subsequently dissolved in water, filtered and freeze dried. Extracts were dissolved in water and their activity determined against eight bacterial species. Plant extracts that showed appreciable antibacterial activity in the initial antimicrobial screen were examined further with both their MICs and MBCs determined. Results: Ten of the sixteen plant extracts showed antimicrobial activity. Extracts of Eucalyptus, Melaleuca, Prostanthera and Westringia were particularly active with MICs as low as 0.25 mg/ml against organisms including P. aeruginosa and S. aureus. Conclusion: The current study demonstrates the antimicrobial activity of plant extracts from temperate Australia. These may serve as precursors for future chemotherapy agents.

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A Survey of Australian Solanum Plants for Potentially Useful Sources of Solasodine

Cited by 29 publications

References 22 publications

Production of steroidal alkaloids by hairy roots of Solanum aviculare and the effect of gibberellic acid

Production of steroidal alkaloids by hairy roots of Solanum aviculare and the effect of gibberellic acid

Genotype-environment interaction in poroporo (Solanum aviculare)

Antimicrobial Activity of Extracts from Native Plants of Temperate Australia

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