A Survey of Analytical Techniques for Noroviruses

Liu, Lingling; Moore, Matthew D.

doi:10.3390/foods9030318

Cited by 31 publications

(29 citation statements)

References 187 publications

(259 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Increasingly, the spectrum of analytical techniques is being widened. Promising developments in the field include biosensors (such as monoclonal antibodies, aptamers, porcine gastric mucin, and HBGAs), investigated for their potential of concentrating noroviruses, microarray-based assays [ 266 ] and omics-based analyses [ 267 , 268 ].…”

Section: Detection and Typing Of Norovirusesmentioning

confidence: 99%

Noroviruses—The State of the Art, Nearly Fifty Years after Their Initial Discovery

Ludwig‐Begall

Mauroy

Thiry

2021

Viruses

View full text Add to dashboard Cite

Human noroviruses are recognised as the major global cause of viral gastroenteritis. Here, we provide an overview of notable advances in norovirus research and provide a short recap of the novel model systems to which much of the recent progress is owed. Significant advances include an updated classification system, the description of alternative virus-like protein morphologies and capsid dynamics, and the further elucidation of the functions and roles of various viral proteins. Important milestones include new insights into cell tropism, host and microbial attachment factors and receptors, interactions with the cellular translational apparatus, and viral egress from cells. Noroviruses have been detected in previously unrecognised hosts and detection itself is facilitated by improved analytical techniques. New potential transmission routes and/or viral reservoirs have been proposed. Recent in vivo and in vitro findings have added to the understanding of host immunity in response to norovirus infection, and vaccine development has progressed to preclinical and even clinical trial testing. Ongoing development of therapeutics includes promising direct-acting small molecules and host-factor drugs.

show abstract

Section: Detection and Typing Of Norovirusesmentioning

confidence: 99%

Noroviruses—The State of the Art, Nearly Fifty Years after Their Initial Discovery

Ludwig‐Begall

Mauroy

Thiry

2021

Viruses

View full text Add to dashboard Cite

show abstract

“…Construction of this plasmonic biosensor made it capable of separating and isolating the target virus from feces in clinical samples by applying the external magnetic field. Furthermore, SPR analysis was utilized to investigate the binding affinity and the associated kinetic of ligands to NOV [ 282 ]. In the LSPR-based biosensor reported by Sam Su Heo [ 108 ], they detected the noroviral capsid proteins as well as human NOVs.…”

Section: Norovirus (Nov)mentioning

confidence: 99%

Role of plasmonics in detection of deadliest viruses: a review

et al. 2021

View full text Add to dashboard Cite

Viruses have threatened animal and human lives since a long time ago all over the world. Some of these tiny particles have caused disastrous pandemics that killed a large number of people with subsequent economic downturns. In addition, the quarantine situation itself encounters the challenges like the deficiency in the online educational system, psychiatric problems and poor international relations. Although viruses have a rather simple protein structure, they have structural heterogeneity with a high tendency to mutation that impedes their study. On top of the breadth of such worldwide worrying issues, there are profound scientific gaps, and several unanswered questions, like lack of vaccines or antivirals to combat these pathogens. Various detection techniques like the nucleic acid test, immunoassay, and microscopy have been developed; however, there is a tradeoff between their advantages and disadvantages like safety in sample collecting, invasiveness, sensitivity, response time, etc. One of the highly resolved techniques that can provide early-stage detection with fast experiment duration is plasmonics. This optical technique has the capability to detect viral proteins and genomes at the early stage via highly sensitive interaction between the biological target and the plasmonic chip. The efficiency of this technique could be proved using commercialized techniques like reverse transcription polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA) techniques. In this study, we aim to review the role of plasmonic technique in the detection of 11 deadliest viruses besides 2 common genital viruses for the human being. This is a rapidly moving topic of research, and a review article that encompasses the current findings may be useful for guiding strategies to deal with the pandemics . By investigating the potential aspects of this technique, we hope that this study could open new avenues toward the application of point-of-care techniques for virus detection at early stage that may inhibit the progressively hygienic threats.

show abstract

“…Many researchers, including chemists, biologists, physicists, engineers, and medical doctors, have used the sensor platforms as an original application in different areas for the development of sensors [61][62][63][64][65]. Today, the early detection of a biological and chemical attack of the threats can only be analyzed with commercial methods.…”

Section: Monitoring Biological and Chemical Threats Agentsmentioning

confidence: 99%

Plasmonic Sensors for Monitoring Biological and Chemical Threat Agents

2020

View full text Add to dashboard Cite

Sensors are excellent options owing to their ability to figure out a large number of problems and challenges in several areas, including homeland security, defense, medicine, pharmacology, industry, environment, agriculture, food safety, and so on. Plasmonic sensors are used as detection devices that have important properties, such as rapid recognition, real-time analysis, no need labels, sensitive and selective sensing, portability, and, more importantly, simplicity in identifying target analytes. This review summarizes the state-of-art molecular recognition of biological and chemical threat agents. For this purpose, the principle of the plasmonic sensor is briefly explained and then the use of plasmonic sensors in the monitoring of a broad range of biological and chemical threat agents is extensively discussed with different types of threats according to the latest literature. A conclusion and future perspectives are added at the end of the review.

show abstract

A Survey of Analytical Techniques for Noroviruses

Cited by 31 publications

References 187 publications

Noroviruses—The State of the Art, Nearly Fifty Years after Their Initial Discovery

Noroviruses—The State of the Art, Nearly Fifty Years after Their Initial Discovery

Role of plasmonics in detection of deadliest viruses: a review

Plasmonic Sensors for Monitoring Biological and Chemical Threat Agents

Contact Info

Product

Resources

About