A Surface Acoustic Wave (SAW) biosensor method for functional quantification of E. coli l-asparaginase

Yao, Han; Fernández, Cristina Soto; Xu, Xiaolong; Wynendaele, Evelien; Spiegeleer, Bart De

doi:10.1016/j.talanta.2019.05.046

Cited by 14 publications

(10 citation statements)

References 37 publications

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“…[41,42] Furthermore, the miniature size of these biosensors also made them highly ideal for the sensing of many biologically active targets such as small cells, DNA, and protein molecules. [42] SAW biosensors have already been demonstrated in scientific community for a broad range of biosensing purposes such as the detection of specific cells, [43][44][45][46] DNA matching [46][47][48][49] as well as for viral [50][51][52][53] and bacteria [54][55][56] detection. Many of these studies had help substantiate the importance of SAW biosensors in the area of biosensing technology amidst the diverse platforms that are available.…”

Section: Lamb Wavesmentioning

confidence: 99%

“…SAW biosensors have already been demonstrated in scientific community for a broad range of biosensing purposes such as the detection of specific cells, [ 43–46 ] DNA matching [ 46–49 ] as well as for viral [ 50–53 ] and bacteria [ 54–56 ] detection. Many of these studies had help substantiate the importance of SAW biosensors in the area of biosensing technology amidst the diverse platforms that are available.…”

Section: Introductionmentioning

confidence: 99%

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Current Trends on Surface Acoustic Wave Biosensors

Zida

Lin

Khung

2021

Adv Materials Technologies

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The development of rapid biosensing platforms is an integral part for the detection of many diseases, as well as important clinical biomarkers. So far, many new biosensing technologies have been described in literature but many of these novel platforms remain noncommercializable due to challenges in fabrication process, operational conditions as well as other cost concerns. Hence, there is a need to develop efficient and cost‐effective biosensing platforms and of the types available from literature, surface acoustic wave (SAW) biosensors have certain standout attributes. The simple manufacturing requirements of SAW‐based biosensor and its wide operating frequency range have produced promising outcome for bio‐detection and this has rendered this technological platform as a serious contender for point‐of‐care biosensor design. So far, SAW devices are reported for the detection of various bioactive targets of clinical importance and several designs are already commercialized. In this review, the latest development of SAW technologies in recent years for the detection of a broad range of biomolecules is presented and some of the challenges as well as potential future developments of SAW biosensors are highlighted.

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Section: Lamb Wavesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Current Trends on Surface Acoustic Wave Biosensors

Zida

Lin

Khung

2021

Adv Materials Technologies

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“…Additionally, the low attenuation of horizontally polarized waves in a liquid medium without considerable acoustic attenuation also provides an added advantage [268,275]. The application of SAW devices in biosensing can thus be extended to multiple fields, such as biomedical applications for detecting a variety of disease biomarkers, tumor cell detection, the study of cell adhesion, detection of pathogens and viruses, and complex biomolecules, including lipopolysaccharides for drug quality test, DNA, levels of glucose, and uric acid in human serum [18,52,55,211,214,[276][277][278]. The bioreceptors can be an antibody, aptamers, or MIPs, or can be oligonucleotides, such as peptide nucleic acid or single-stranded DNA (ssDNA) [254,276,279,280].…”

Section: Applications Of Saw In Biosensingmentioning

confidence: 99%

“…Apart from the disease biomarkers, SAW biosensors have also been reported for the detection of complex biomolecules, such as toxins, glucose, and uric acid in human serum; intracellular pH monitoring; and tetrameric enzymes used in cancer treatment [18,52,211,277]. Marine toxins, such as okadaic acid (OA) and bacterial toxins, such as endotoxin, have been detected using a Love wave sensor [55,294].…”

Section: (I) Protein and Biomolecular Detectionmentioning

confidence: 99%

Acoustic Biosensors and Microfluidic Devices in the Decennium: Principles and Applications

Nair

Teo

2021

Micromachines

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Lab-on-a-chip (LOC) technology has gained primary attention in the past decade, where label-free biosensors and microfluidic actuation platforms are integrated to realize such LOC devices. Among the multitude of technologies that enables the successful integration of these two features, the piezoelectric acoustic wave method is best suited for handling biological samples due to biocompatibility, label-free and non-invasive properties. In this review paper, we present a study on the use of acoustic waves generated by piezoelectric materials in the area of label-free biosensors and microfluidic actuation towards the realization of LOC and POC devices. The categorization of acoustic wave technology into the bulk acoustic wave and surface acoustic wave has been considered with the inclusion of biological sample sensing and manipulation applications. This paper presents an approach with a comprehensive study on the fundamental operating principles of acoustic waves in biosensing and microfluidic actuation, acoustic wave modes suitable for sensing and actuation, piezoelectric materials used for acoustic wave generation, fabrication methods, and challenges in the use of acoustic wave modes in biosensing. Recent developments in the past decade, in various sensing potentialities of acoustic waves in a myriad of applications, including sensing of proteins, disease biomarkers, DNA, pathogenic microorganisms, acoustofluidic manipulation, and the sorting of biological samples such as cells, have been given primary focus. An insight into the future perspectives of real-time, label-free, and portable LOC devices utilizing acoustic waves is also presented. The developments in the field of thin-film piezoelectric materials, with the possibility of integrating sensing and actuation on a single platform utilizing the reversible property of smart piezoelectric materials, provide a step forward in the realization of monolithic integrated LOC and POC devices. Finally, the present paper highlights the key benefits and challenges in terms of commercialization, in the field of acoustic wave-based biosensors and actuation platforms.

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“…Conversely, label-free bioanalysis technologies eliminate labeling or tagging procedures, thus allowing the use of natural biomolecules that are suitable for numerous applications in the biomedical field [1][2][3][4]. Various label-free analytical techniques have been reported, involving the use of the quartz crystal microbalance [5], biolayer interferometry [6], surface acoustic waves [7], silicon nanowires [8], and surface plasmon resonance (SPR) [9]. Among them, there has been significant interest in biosensors based on SPR owing to their inherently attractive features, such as rapid detection in real time and the possibility of on-chip integration for smart sensor systems [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Recent Advancements in Aptamer-Based Surface Plasmon Resonance Biosensing Strategies

Chang

2021

Biosensors

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Surface plasmon resonance (SPR) can track molecular interactions in real time, and is a powerful as well as widely used biological and chemical sensing technique. Among the different SPR-based sensing applications, aptamer-based SPR biosensors have attracted significant attention because of their simplicity, feasibility, and low cost for target detection. Continuous developments in SPR aptasensing research have led to the emergence of abundant technical and design concepts. To understand the recent advances in SPR for biosensing, this paper reviews SPR-based research from the last seven years based on different sensing-type strategies and sub-directions. The characteristics of various SPR-based applications are introduced. We hope that this review will guide the development of SPR aptamer sensors for healthcare.

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A Surface Acoustic Wave (SAW) biosensor method for functional quantification of E. coli l-asparaginase

Cited by 14 publications

References 37 publications

Current Trends on Surface Acoustic Wave Biosensors

Current Trends on Surface Acoustic Wave Biosensors

Acoustic Biosensors and Microfluidic Devices in the Decennium: Principles and Applications

Recent Advancements in Aptamer-Based Surface Plasmon Resonance Biosensing Strategies

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