A successfully treated case of peritonitis due to Fusarium dimerum

Fusarium solani infection after antimicrobial treatment of a severe bacterial peritonitis: a case report and review of the literature

“…are relatively resistant to many antifungal agents, including 5-flucytosine, and the susceptibility to other drugs differs among species. 7,13,14 In this case, Fusarium solani strain was resistant to numerous antifungals, including all tested triazoles and the alylamine derivative terbinafine. On the other hand, liposomal amphotericin B treatment, which is considered the drug of choice, was successfully used.…”

“…Although they are rarely responsible to cause disease in immunocompetent humans, recently, they emerged as significant opportunistic pathogens often associated with fatal outcome in immunocompromised subjects, in particular those with hematological malignancies. 7,10 Fusarium peritonitis in continuous peritoneal dialysis patients has been rarely reported in the literature. 7,[13][14] Important risk factors for Fusarium infection are compromised immune system, tissue damages after trauma and presence of foreign bodies.…”

“…7,10 Fusarium peritonitis in continuous peritoneal dialysis patients has been rarely reported in the literature. 7,[13][14] Important risk factors for Fusarium infection are compromised immune system, tissue damages after trauma and presence of foreign bodies. 10 In subjects undergoing continuous ambulatory PD, Fusarium spp.…”

“…can determine either plugging or invasion of the peritoneal catheter, thus leading to fungemia, as previously reported. 7,10,14 Other risk factors associated with fungal peritonitis are previous episodes of bacterial peritonitis, wide-spectrum antibiotic treatments, advanced age, administration of immunosuppressant therapy and hospitalization. 3 In this case, different factors might have contributed to the development of Fusarium infection, despite the relative young age and previous good health status of the patient.…”

“…[3][4][5][6] About 60-90% of fungal peritonitis are due to Candida species, in particular Candida parapsilosis, while infections due to other yeasts or filamentous moulds have been rarely reported. 3,6,7 Filamentous fungi are widely distributed in nature. Among them, strains of Aspergillus genus and Penicillium species are the most frequent isolates causing peritonitis in PD patients.…”