A Study of Tuberculosis Infection in Workers at a University General Hospital: Associated Factors and Evolution in 20 Years

Assessing the Prevalence of Latent Tuberculosis among Health Care Providers in Zagazig City, Egypt Using Tuberculin Skin Test and QuantiFERON-TB Gold In-Tube Test

“…On the other hand, a higher percentage (59.1%) of our sample was positive for latent tuberculosis infection by Tuberculin skin test. This was comparable to Costa et al (17) who found out 44.4% and another study from Switzerland which reported 48% (18). The difference between QFT-GIT (28.8%) and Tuberculin skin test (59.1%) was in accordance with similar previous studies (1,19).…”

Incidence of tuberculosis infection among healthcare workers: Risk factors and 20-year evolution

“…The introduction of a specific LTBI surveillance program among HCWs in our hospital has permitted us to analyse baseline LTBI prevalence, which was 25.7%, up to 44.2% at the beginning of the study period (1988e1992) to 15.5 at the end of this period (2003e2007). 9 The classical screening test in surveillance protocols for HCWs with workplace exposure to TB is tuberculin skin test. 2 In recent years a new test appeared based on detection of interferon gamma (IFN-g) released as a response to the in vitro stimulation of T cells from peripheral blood sensitized with specific antigens of M. tuberculosis.…”

Serum levels of inhibitory costimulatory molecules and correlations with levels of innate immune cytokines in patients with pulmonary tuberculosis

“…The development of tuberculosis after MTB infection also depends on nonbiological factors such as sex, age, socioeconomic status, 21 living environment, 22 and lifestyle factors such as smoking 23 and drinking alcohol. 24 In view of this, we analyzed the factors influencing PTB and levels of immune molecules in this study.…”