Search citation statements
Paper Sections
Citation Types
Year Published
Publication Types
Relationship
Authors
Journals
FIFTEEN FIGURESThe brow11 iiigninal glands of the rabbit are branched tubnlar, meroci*iiie glaiicls, wliich secrete a maloclorous liqnicl which imparts to tliese ariinials their characteristic odor. The morphology and the biology of these organs is little linon-ii altliougli they m r e studied by Leyclig (1850), Scliaap (1899), Ranther ( '03), a i d Disselhorst ( '04). This paper presents a detailed accoiint of the histology, cytology, and cyto-clieniistry of the glands of normal males of different ages. MATERIAL AND METHODSThe browii inguinal glands were removed from 28 normal inale laboratory rabbits: 4 newborn and 4 each at ages of 2 weeks, 2 months, 3 months and 5 months ; 8 animals from 7 months to 2 years. One year-old male, castrated when 6 weeks old, ivas also used. The glaiids from 6 adult fernales were coiiipared with those of males.Saiiiple histological preparations of tissues fixed in Bo~iiri's fluid and stained with hematosylin and eosin were made from the glands of all the animals used. Tissues fixed in Bodiaii's fixer no. 2 were treated with the protargol metliod of Bodian.Otlier siinilarly fixed sections were treated with tlmnioniacal silsver nitrate and with diamine silver hydroxide.F o r the clemonstration of sulfliydi-yl groups, fresh f ragrrierits of glaiids 01-frozen sections of tissues fised in formolcalcium not loiiger than two hours were treated with the nitro-This vork was supported in part hg x grant froin the Piiited States Public TTealth Service, RG 2125. 413
FIFTEEN FIGURESThe brow11 iiigninal glands of the rabbit are branched tubnlar, meroci*iiie glaiicls, wliich secrete a maloclorous liqnicl which imparts to tliese ariinials their characteristic odor. The morphology and the biology of these organs is little linon-ii altliougli they m r e studied by Leyclig (1850), Scliaap (1899), Ranther ( '03), a i d Disselhorst ( '04). This paper presents a detailed accoiint of the histology, cytology, and cyto-clieniistry of the glands of normal males of different ages. MATERIAL AND METHODSThe browii inguinal glands were removed from 28 normal inale laboratory rabbits: 4 newborn and 4 each at ages of 2 weeks, 2 months, 3 months and 5 months ; 8 animals from 7 months to 2 years. One year-old male, castrated when 6 weeks old, ivas also used. The glaiids from 6 adult fernales were coiiipared with those of males.Saiiiple histological preparations of tissues fixed in Bo~iiri's fluid and stained with hematosylin and eosin were made from the glands of all the animals used. Tissues fixed in Bodiaii's fixer no. 2 were treated with the protargol metliod of Bodian.Otlier siinilarly fixed sections were treated with tlmnioniacal silsver nitrate and with diamine silver hydroxide.F o r the clemonstration of sulfliydi-yl groups, fresh f ragrrierits of glaiids 01-frozen sections of tissues fised in formolcalcium not loiiger than two hours were treated with the nitro-This vork was supported in part hg x grant froin the Piiited States Public TTealth Service, RG 2125. 413
The correlation between changes in the cell organelles and the processes of storage and secretion is one of the fundamental problems of cytology. I n the liver many of the activities of the cell are known through biochemical studies, and in certain instances the products of these activities-e.g. bile acids, glycogen, and fat-can be demonstrated histologically. Several suggestions have appeared in the literature of interrelationships between the organelles and the processes associated with alimentation, but no comprehensive study has been undertaken. The present investigation is such a study of the relationship between changes in the mitochondria and the Golgi substance on the one hand and the secretion of bile acids and the storage of glycogen and fat on the other.Recently Forsgren ( '35) and his associates have described reciprocal diurnal cycles in the deposition of glycogen and in the secretion of the bile components (actually the bile acids, because of the method of demonstration). According to their observations the greatest amount of glycogen is present in the liver during the night, whereas the largest amount of bile acid material is secreted during the afternoon. Except ' A portion of a thesis submitted in partial fulfillment of the requirements for a Horton-Hallowell Fellow of Wellesley College, 1942-43. the degree of Doctor
TWO PLATES (TWELVE FIGURES)The liver of the fetal mammal performs many functions, including the storage of glycogen and fat and the secretion of bile pigments (Feldman, '20 ; Stieve and Kaps, '37). After birth the liver undergoes 1 A portion of a thesis submitted in partial fulfillnir~nt of the requirements for the degree of Doctor of Philosophy at Brown Trnirersity, Srptrmher, 1943.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.