A Simplified Green Chemistry Approach to the Biginelli Reaction Using “Grindstone Chemistry”.

Abstract

For Abstract see ChemInform Abstract in Full Text.

Ultrasound Promoted Green and Facile One‐Pot Multicomponent Synthesis of 3,4‐dihydropyrano[c]chromene Derivatives

“…All yields refer to the precipitated products. All the products were characterized by 1 H NMR, 13 C NMR, IR, and EI-Mass analysis and were found to be in good agreement with those reported in the literature. e 1 H NMR (500 MHz) and 13…”

“…Green chemistry in recent times has gained immense attention and played a signi�cant role in revolutionizing synthetic organic chemistry to minimize the usage of organic solvents and their disposal thereby developing environmentfriendly organic synthesis [13]. In this context, water has been explored in several synthetic methodologies as an efficient solvent which successfully displaced the usage of harmful organic solvents thereby reducing the generation of hazardous wastes [14].…”

“…All the obtained products were characterized by comparing their physical data with the authentic samples. Hz, H Ar ), 7.91 (1H, d, Hz, H Ar ) ppm 13. C NMR (125 MHz, DMSO-d ): 58.18, 104.88, 114.84, 117.44, 121.10, 123.34, 125.64, 127.99, 128.50, 129.59, 132.79, 145.21, 153.56, 154.79, 158.86, 161.41 ppm.…”

Use of different Fruit juices as a Catalyst in Various Organic Synthesis (A Sustainable Development of Chemistry)

“…A reaction always should consume less energy i.e. supported by grinding technique [6], micro-wave [7] or ultrasound [8] irradiation with excellent yield of the product. This article summarizes use of various fruit juices as a bio-catalyst in number of organic syntheses such as formation of Dihydropyrimidones/Dihydrothipyrimidone,Triazoles through multicomponent reactions (Pineapple/lemon/Tamarind juice),formation of bis, trisindolylmethanes ( grape and tamarind juice), bis di (indolyl) methane (tamarind juice).These protocols are having simple workup procedure with good yield and more over environmentally benign.…”

Green Preparation and Structure Elucidation of Spiro Indole Derivatives Using Grindstone Technique

“…Required activation energy is provided from friction of the reacting molecules. 2 It is not only advantageous from the environmental point of view but also offers rate enhancement, less waste products and higher yields. Such reactions are simple to handle, reduce pollution, and comparatively cheaper to operate.…”