Silver nanoparticles are one of the most studied compounds in materials science due to their antimicrobial efficacies and, for instance, in photocatalysis, dye-sensitised solar cells, and biomedical devices. However, conventional methods of synthesis of silver nanoparticles (AgNPs) require hazardous and costly chemicals, and a large amount of energy is expended. In this review, efforts have been made to target where eco-friendly synthetic techniques are being conducted using various plant extract to develop nanoparticles in inexpensive, easily scaled up, and environmentally benign. These findings are stimulated intense research activities that focused on synthesis, modification, properties, and applications of these ecofriendly nanoparticles. This review covers all these aspects, such as the biological routes for the synthesis of nanoparticles employed to synthesis the nano-silver using algae, bacteria, plants, fungi, etc. Also, the chemical positions and possible traditional uses of the plants are enlisted.
As there is no specified drug available to fight COVID-19, it is essential to have a different strategy to fight this virus. In the present study, using molecular docking, we have identified possible protease inhibitors of COVID-19 by the molecules present in Nigella sativa L. (black cumin), which is a reputed healing herb extensively used for processing Ayurvedic and Unani remedies. Herein, we perform molecular docking and study of various physical properties/descriptors of four derivatives of thymoquinone found in the essential oil of the said seeds and they are compared with the docking results of chloroquine to determine its potential against COVID-19 infection.
COVID-19, which is instigated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused the pandemic. This disease provoked with its epicenter in China. Belonging to the Coronaviridae family of viruses, it is a new strain of β type of coronavirus. The World Health Organization (WHO) declared its name as 'SARS-CoV-2'. In January 2020, the WHO declared COVID-19 as the sixth public-health emergency of international suffering. Lack of etymology, precautionary measures, specified drug or vaccination for this viral infection was the main reason for the epidemic. Hence, there was an extensive need for the scientists throughout the globe to work on it. Some potential inhibitors have been reported to possibly treat COVID-19 affected patients. Likewise, a new technique, which is the Plasma Therapy, is used in the treatment. In this context, this review aims to summarize the epidemiology, virology, mode of dissemination, diagnosis, treatment, and prevention measures of COVID-19.
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