A Self-Association Cross-Linked conductive zwitterionic hydrogel as a myocardial patch for restoring cardiac function

Wearable and Flexible Hydrogels for Strain Sensing and Wound Electrical Stimulation

“…As mentioned previously, the conductivity of DC-Gel-PAM-3 hydrogels is 0.385 S/m, which matches the conductivity of certain human tissues, such as natural spinal cord tissue with conductivity ranging from ref and natural cardiac myocytes with conductivity consistently around values from ref . We therefore attempted to use DC-Gel-PAM-3 hydrogel as a conductive medium for electrical stimulation and provided electrical stimulation with P­(VDF-TrFE) piezoelectric membranes from our previous work, and we performed experiments on the repair of whole skin defects in rats.…”

“…In the range of 0.1−100 Hz tested, it can be seen that the G′ of each group of hydrogels is significantly larger than G″, indicating that the prepared hydrogels show solid-like properties, implying that the hydrogels are stable three-dimensional network structures. 17,18 In addition, the G′ and G″ of the hydrogels increased with increasing shear frequency, which was a result of the viscoelasticity of the hydrogels. With the addition of gelatin, Gel-PAM had greater G′ and G″ than PAM, indicating a more stable and rigid double-network structure after the introduction of gelatin.…”

Ultra-robust, high-adhesive, self-healing, and photothermal zwitterionic hydrogels for multi-sensory applications and solar-driven evaporation

“…Due to the balanced stress and strain values, the toughness of PSBMA-LM@PDA hydrogels was well maintained and a maximum toughness of 7.3 MJ m À3 (PSBMA-LM@PDA-2) can be achieved. Overall, our PSBMA-LM@PDA hydrogels exhibited extraordinary mechanical properties with a tensile strength up to 1.3 MPa, a strain up to 1555% and a toughness up to 7.3 MJ m À3 , superior or comparable to those exhibited by most zwitterionic hydrogels 15,[37][38][39][40][41][42][43][44][45][46][47][48][49] (Fig. 2f and Table S1, ESI †).…”

Zwitterionic Conductive Hydrogel-Based Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration in Rats

“…Our previous study and other literature have proved that hydrogels containing zwitterion could down-regulate the expression of inflammatory factors in tissues due to the excellent antifouling properties of the zwitterionic polymers. 23,41 Meanwhile, one study demonstrated that pSBMA hydrogels could accelerate wound healing by promoting macrophage polarization to the M2 type, collagen deposition, and angiogenesis. 42 A satisfactory microenvironment is essential for the regeneration of nerve tissue.…”