A Scientometrics Analysis and Visualization of Depressive Disorder

Xu, Dong; Wang, Yilun; Wang, Kun-Tang; Wang, Yue; Dong, Xinran; Tang, Jie; Cui, Yuan‐Lu

doi:10.2174/1570159x18666200905151333

Cited by 62 publications

(49 citation statements)

References 168 publications

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“…CiteSpace is a freely available Java application for the visualization and analysis of scientific literature trends and patterns ( 27 ). It was created by Professor Chaomei Chen in 2004 and has become popular globally to present the structure, laws, and distribution of scientific knowledge and provide a comprehensive overview of the research situation ( 28 ).…”

Section: Methodsmentioning

confidence: 99%

Emerging trends and hot spots in autoimmune thyroiditis research from 2000 to 2022: A bibliometric analysis

Yang

et al. 2022

Front. Immunol.

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BackgroundAutoimmune thyroiditis (AIT) is the most common autoimmune disease, affecting 3-5% patients worldwide. In recent years, approximately 200 articles on AIT have been published annually in various journals. However, to date, no article has systematically assessed the related literature. Therefore, we conducted a bibliometric analysis on AIT to reveal the dynamic scientific developments and help researchers gain a global perspective while exploring the hotspots and development trends.MethodsAIT-related articles and reviews from 2000 to 2022 were retrieved from the Web of Science Core Collection (WoSCC). The following search terms were used to extract document data: TS= (“ autoimmune thyroiditi*”) OR TI= (“chronic lymphocytic thyroiditi*”) OR TI=(hashimoto*) OR TI= (“postpartum thyroiditis”). We selected articles and reviews published in English from 2000 to 2022. Three software programs (VOSviewer, CiteSpace, Pajek) were employed to analyze the contribution and co-occurrence relationships of different references, countries/regions, institutes, journals and also keywords in this field.ResultsThis scientometric study included 2290 English papers published in 723 journals with 39661 co-cited references from 561 institutions in 120 countries/regions. Based on the reference and keyword analysis, researchers used to focus on “apoptosis”, “insulin resistance”, “encephalopathy”, “IFN-γ” related to AIT during the past 20 years. However, with the development of other novel directions such as “papillary thyroid cancer” (2018-2022), “Vitamin D” (2016-2022), “oxidative stress” (2018-2022), “polymorphism” (2019-2022) and “association” (2020-2022), researchers are more interested in the relationship between papillary thyroid carcinoma and AIT, the effect of vitamin D supplementation on AIT, the oxidative stress in thyroid disease as well as the influence of polymorphism.ConclusionBibliometric analysis of the outputs of AIT shows an overview of the current status of the research on AIT. The associations between papillary thyroid carcinoma, vitamin D, oxidative stress, polymorphism and AIT are major research frontiers. However, further research and collaboration are still required worldwide. Our findings can help researchers grasp the research status of AIT and quickly determine new directions for future research.

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Section: Methodsmentioning

confidence: 99%

Emerging trends and hot spots in autoimmune thyroiditis research from 2000 to 2022: A bibliometric analysis

Yang

et al. 2022

Front. Immunol.

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“…CUMS was applied to construct a mouse model of depression and mice were first separated into following groups: CUMS group, CUMS + n‐3 PUFAs group, CUMS + normal saline (NS) group and control group. Following stressors were used to induce mice in CUMS group 1 : water deprivation (24 h), 2 fasting (24 h), 3 overnight illumination, 4 cage tilting (45°), 5 wet sawdust (100 g sawdust padding with 200 ml water), 6 contact with foreign matter, 7 reversal of light and dark cycles, 8 overhang (10 min), 9 exposure to an empty bottle, 10 tail pinch (1 min, 1 cm from the root of the tail), 11 shaking (5 min), and 12 white noise. Steps mentioned above were randomly arranged to guarantee the unpredictability of the test and lasted for 5 weeks.…”

Section: Methodsmentioning

confidence: 99%

“…In severe cases, it could even lead to suicidal behaviors. 1 The pathogenesis of depression is complex, involving multisystem and multilink dysfunction. And its incidence is mostly believed to be caused by the interaction of social, environmental and individual factors.…”

Section: Introductionmentioning

confidence: 99%

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n‐3 polyunsaturated fatty acids improve depression‐like behavior by inhibiting hippocampal neuroinflammation in mice via reducing TLR4 expression

Zeng

Yang

et al. 2022

Immunity Inflam & Disease

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Introduction n‐3 polyunsaturated fatty acids (PUFAs) are believed to be implicated in the pathogenesis of many inflammation‐related diseases, including depression. Methods The mouse model of depression was established through chronic unpredictable mild stress (CUMS), the mice were intervened with n‐3 PUFAs, and then the expression of toll‐like receptor 4 (TLR4) was stimulated with lipopolysaccharides (LPS). Tail suspension test (TST), forced swimming test (FST) and sucrose preference test were performed to monitor the depression behavior of mice. Microglia activation was detected by Iba1 immunofluorescence, and neuronal injury was detected by Nissl staining. Concentrations of tumor necrosis factor (TNF)‐α, Interleukin (IL)‐6 and IL‐1β in the hippocampus were assessed via enzyme linked immunosorbent assay (ELISA). Quantitative real time polymerase chain reaction was used to detect IL‐6, IL‐1β and TNF‐α messenger RNA levels. Western blot was utilized for detection of TLR4 protein expression. Results CUMS significantly reduced the sucrose preference in mice, while increased the immobility time in FST and TST. Moreover, CUMS significantly aggravated microglia activation and neuronal damage in mice and increased the levels of IL‐6, IL‐1β and TNF‐α in hippocampal tissues, however, intervention with n‐3 PUFAs could improve the above effects. Further, the increased TLR4 induced by LPS partially reversed the inhibition of n‐3 PUFAs on depression‐like behaviors, microglial activation and inflammatory injury of hippocampal neurons. Conclusion n‐3 PUFAs may ameliorate depression‐like behaviors via reducing hippocampal neuroinflammation in CUMS‐induced mice by regulating TLR4 expression, suggesting that n‐3 PUFAs may be an effective antidepressant, which provides evidence for future treatment of depression.

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“…11 There is a wide application of bibliometric analysis today in a number of fields, including depressive disorder, pyroptosis, and electrochemiluminescence sensing technology. [12][13][14] There are, however, no summaries and evaluations of literature characteristics, research directions, research depth, and hotspots on the relationship between COPD and lung carcinomas. In order to provide a reference for future research, it is necessary to determine the current status of the relationship between COPD and lung carcinomas as a whole.…”

Section: Introductionmentioning

confidence: 99%

Study on Chronic Obstructive Pulmonary Disease and Lung Cancer: Web of Science-Based Bibliometric and Visual Analysis

Xu¹,

Wang²,

Zhang³

et al. 2022

IJGM

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Chronic obstructive pulmonary disease (COPD) is one of the main risk factors for lung carcinomas. This study aimed to analyze and construct a model to assess scientific publications on the relationship between COPD and lung carcinomas. Patients and Methods: A literature search of the Web of Science database was performed for publications until November 2, 2021. Microsoft Excel and CiteSpace software were used to perform bibliometric and visual analysis of source journals, countries/regions, institutions, authors, research areas, and hot topics of selected publications. Results: A total of 2175 publications on the relationship between COPD and lung carcinomas were identified. The annual number of papers published and the total annual citation frequency in the field of COPD and lung carcinoma show an upward trend, and the current research hot topics are health, disease risk factors, disease burden, prevention and serious complications. The top three countries/regions with the number of published articles are the United States, China, and the United Kingdom. The author with the most signatures was Castaldi PJ of USA, followed by Xian JF of China. The lack of multinational/regional multi-center research illustrated that the distribution of research forces is unbalanced. Conclusion:According to this study, researchers can identify hot topics and explore new research directions in research of the relationship between COPD and lung carcinomas.

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A Scientometrics Analysis and Visualization of Depressive Disorder

Cited by 62 publications

References 168 publications

Emerging trends and hot spots in autoimmune thyroiditis research from 2000 to 2022: A bibliometric analysis

Emerging trends and hot spots in autoimmune thyroiditis research from 2000 to 2022: A bibliometric analysis

n‐3 polyunsaturated fatty acids improve depression‐like behavior by inhibiting hippocampal neuroinflammation in mice via reducing TLR4 expression

Study on Chronic Obstructive Pulmonary Disease and Lung Cancer: Web of Science-Based Bibliometric and Visual Analysis

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