A review of chemotherapeutic plaque control

Johnson, Robert; J, Rozanis

doi:10.1016/0030-4220(79)90168-3

Cited by 22 publications

(2 citation statements)

References 55 publications

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“…Methods for plaque control which are easier to perform than tooth brushing and interdental cleaning have been tested, either as a substitute or as a supplement to the mechanical oral hygiene procedures. Vaccines, enzymes, antibiotics and antiseptics have been evaluated for their antiplaque effectiveness (for review see Loesche 1976, Johnson & Rozanis 1979, Lang 1980, Tehranidad 1980, Hull 1980, Kornman 1985.…”

Section: Introductionmentioning

confidence: 99%

The effect of chlorhexidine and Octapinol®on early human plaque formation. A light and electron microscopic study

Brecx¹,

Theilade²,

Attström³

et al. 1987

J of Periodontal Research

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The influence of chlorhexidine and Octapinol® on early plaque formation in humans was assessed in vivo. Three subjects with healthy gingiva were used. Plastic films were applied to the buccal surfaces of the maxillary right first premolars and plaque was allowed to form for either 4 or 24 hours. After 1 minute of plaque development, a drop of water, 1 % chlorhexidine or 1 % Octapinol was gently applied in situ; in the 24‐h experiment an additional drop was added at 12 h. In total, 76 films were obtained, with a comparable number of specimens in each of the 6 groups. The samples were processed for light and transmission electron microscopy, using standardized techniques for area sampling and cell counting. All control films were covered by a surface coating of acellular material in or on which bacteria, epithelial cells and leukocytes were observed. The controls and to a lesser extent the Octapinol samples exhibited a significant increase in bacterial count between 4 and 24 h. However, the number of bacteria in the chlorhexidine samples showed only a slight increase within this period. Some microorganisms in the chlorhexidine samples appeared to be undergoing degeneration. In the Octapinol specimens the bacterial morphology was generally intact with many extracellular areas of high electron density. Chlorhexidine and Octapinol both had a qualitative effect on early plaque formation, but only the former had a detectable quantitative effect at this initial stage of plaque accumulation.

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Section: Introductionmentioning

confidence: 99%

The effect of chlorhexidine and Octapinol®on early human plaque formation. A light and electron microscopic study

Brecx¹,

Theilade²,

Attström³

et al. 1987

J of Periodontal Research

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“…The use of oral chemotherapy was introduced many years ago (Loesche 1976;Johnson & Rozanis 1979). The main purpose of a chemotherapeutic agent is to control the oral plaque or periodontopathogenic bacteria and return a symbiotic state (Hajishengallis & Lamont 2012;Marsh 1994;Moore & Moore 1994).…”

Section: Antimicrobial Plaque Controlmentioning

confidence: 99%

Clinical and microbiological aspects of periodontal disease in horses in South-East Queensland, Australia

Chinkangsadarn¹

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The study of periodontal disease as part of equine dentistry is one of the overlooked fields of study, which truly needs more study and research to clearly understand the nature of the disease, the most appropriate diagnostic technique and prevention or treatment to provide for a good quality of life for horses.The abattoir survey of the oral cavity and dentition of 400 horses from SouthEast Queensland, Australia, showed that the most common dental abnormality was sharp enamel points (55.3% prevalence). Several types of dental abnormalities were strongly associated with age. The highest frequency of dental abnormalities (97.5%) were observed in senior horses (11-15 years old) and this included periodontal disease that increased to almost fifty percent in senior horses. The findings also confirmed that all horses, not just young horses, should have regular complete dental examinations as early as possible which should limit the development of more severe dental pathologies later in life.The equine oral microbiome found in dental plaque can cause oral disease which involves the some of the endogenous oral microbiota becoming opportunistic pathogens. The conventional method of oral microbiology based on culture dependent techniques usually overestimates the significance of species that are easily grown and overlooks microbial community diversity. Recently, the culture independent techniques using the next generation sequencing (NGS) method can determine the whole bacterial microbiota. The results from culture dependent and NGS method of analysis of healthy gingiva and periodontitis samples showed that the most common Genera isolated were Prevotella and Porphyromonas without a statistical significance in bacterial diversity, between the control and periodontitis groups. In conclusion, equine bacterial diversity between the healthy and periodontitis groups were similar which is different from other animals and this may be due to factors such as dentition, feed type and husbandry.The standard approach for diagnosis of equine periodontal disease (EPD) is based on clinical dental examination but to evaluate the current stage of disease and for further treatment planning, auxiliary aids such radiography are required. Equine dental radiography has been largely restricted to extraoral techniques by the standard equine radiography technology and the complexity of equine head anatomy. In III addition, superimposition and distortion of the cheek teeth arcade is a major problem for radiographic interpretation. Intraoral radiography has been largely ignored in horses, due to the uncooperative nature of these patients and the absence of dedicated technology unsuitable for equine oral radiography. In this study, radiographic images from seven horse heads obtained using a commercially available equine intraoral computed radiography system (IO-CR) and 3D imaging from computed tomography file sets were reviewed. IO-CR has shown potential as a diagnostic tool where key pathological lesions of EPD of the cheek teeth were demon...

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Dental bacterial plaque

Laird

Grant

1983

International Journal of Biochemistry

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A review of chemotherapeutic plaque control

Cited by 22 publications

References 55 publications

The effect of chlorhexidine and Octapinol®on early human plaque formation. A light and electron microscopic study

The effect of chlorhexidine and Octapinol®on early human plaque formation. A light and electron microscopic study

Clinical and microbiological aspects of periodontal disease in horses in South-East Queensland, Australia

Dental bacterial plaque

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