A review and an update of cystic ovarian degeneration in ruminants

López-Dı́az, Miguel; Bosu, W.T.K.

doi:10.1016/0093-691x(92)90173-o

Cited by 88 publications

(64 citation statements)

References 78 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This occurs in approximately 20-30% of the ewes (GONZALEZ-BULNES et al, 2000). A possible cause may a deficient or inexistent preovulatory LH surge (GONZALEZ-BULNES et al, 2003) or the presence of non-responsive follicles due to a downregulation of the granulosa and theca LH receptors (LOPEZ-DIAZ & BOSU, 1992). COGNIÉ et al (1986) suggested that the administration of LH at the end of SOV treatment with exogenous FSH might increase the ovulation rate and the number of recovered embryos.…”

Section: Sincroniza O Tempo Das Ovulações E Incrementa a Taxa De Ovulmentioning

confidence: 99%

Does supplemental LH changes rate and time to ovulation and embryo yield in Santa Ines ewes treated for superovulation with FSH plus eCG?

et al. 2012

View full text Add to dashboard Cite

Section: Sincroniza O Tempo Das Ovulações E Incrementa a Taxa De Ovulmentioning

confidence: 99%

Does supplemental LH changes rate and time to ovulation and embryo yield in Santa Ines ewes treated for superovulation with FSH plus eCG?

et al. 2012

View full text Add to dashboard Cite

“…The disease process is a consequence of failure of a mature follicle to ovulate at the appointed time during the estrous cycle [1]. Follicular cysts are reportedly caused by an endocrine imbalance in the hypothalamo-hypophyseal-gonadal axis [2][3][4]. Inappropriate productions of LH, steroid hormones and steroid synthesizing enzymes have been observed in cows with cystic follicles [3][4][5][6][7][8][9][10].…”

mentioning

confidence: 99%

Deficient Proliferation and Apoptosis in the Granulosa and Theca Interna Cells of the Bovine Cystic Follicle

Isobe

Yoshimura

2007

J. Reprod. Dev.

View full text Add to dashboard Cite

Abstract. The aim of the present study was to examine the frequencies of cell proliferation and death of granulosa and theca interna layers during development of cystic follicles in order to understand the mechanisms of cystic follicle formation. Paraffin sections of cystic follicles were immunostained with antibodies against proliferating cell nuclear antigen (PCNA) and cleaved caspase-3 in order to observe proliferating and apoptotic cells, respectively. The concentrations of estradiol-17β and progesterone in the follicular fluid of these follicles were measured by ELISA. The granulosa and theca interna layers contained both PCNA-and caspase-3-positive cells, although their numbers were limited. There was significant negative correlation between the estradiol-17β and progesterone concentrations in the follicular fluid. Regression analysis revealed no significant correlation, except for that between the PCNA-positive cells in the theca interna and the caspase-3-positive cells in the granulosa layer. These results indicate that the granulosa and theca interna cells of the cystic follicle show weak proliferative activity and low apoptotic frequency; this implies that the cystic follicle grows slowly and then maintains a static condition without degeneration, which leads to long-term persistence of the follicle.

show abstract

“…Dev. 52: [1][2][3][4][5][6][7][8][9][10][11]2006) ollicular cysts in cattle are characterized by the persistence of anovulatory follicular structures in the absence of corpora lutea, with interruption of normal estrous cycles [1][2][3][4]. In many countries, including Japan, follicular cysts affect a high proportion of dairy cows and cause economic losses to the dairy industry by extending the int e r v a l f r o m c a l v i n g t o c o n c e p t i o n .…”

mentioning

confidence: 99%

Formation of Follicular Cysts in Cattle and Therapeutic Effects of Controlled Internal Drug Release

Todoroki

Kaneko

2006

Journal of Reproduction and Development

View full text Add to dashboard Cite

Abstract. Follicular cysts in cattle result from excessive growth of the dominant follicle without ovulation and still constitute a major reproductive disorder in this species. One key hormonal characteristic of cows with follicular cysts is the lack of an LH surge, although they have increased plasma estradiol concentrations. Another is a relatively high level of pulsatile secretion of LH that promotes continued growth of the dominant follicle. These LH characteristics seem to result from a functional abnormality in the feedback regulation of LH secretion by estradiol. Treatment with controlled internal drug release devices that increase circulating progesterone levels is effective in resolving follicular cystic conditions by 1) lowering pulsatile LH secretion and 2) restoring the ability of the hypothalamo-pituitary axis to generate an LH surge in response to an increase in circulating estradiol.

show abstract

A review and an update of cystic ovarian degeneration in ruminants

Cited by 88 publications

References 78 publications

Does supplemental LH changes rate and time to ovulation and embryo yield in Santa Ines ewes treated for superovulation with FSH plus eCG?

Does supplemental LH changes rate and time to ovulation and embryo yield in Santa Ines ewes treated for superovulation with FSH plus eCG?

Deficient Proliferation and Apoptosis in the Granulosa and Theca Interna Cells of the Bovine Cystic Follicle

Formation of Follicular Cysts in Cattle and Therapeutic Effects of Controlled Internal Drug Release

Contact Info

Product

Resources

About