A retrospective study of 171 patients with oral lichen planus in the East Bohemia - Czech Republic – single center experience

Abstract

Objectives: Oral lichen planus is chronic inflammatory disease with a high prevalence in the population. This study describes the epidemiological and clinical characteristics of group of patients with oral lichen planus in the Czech Republic. Material and Methods: Data was taken from the medical records of 171 patients referred to the Oral Medicine Unit at the University Hospital in Hradec Králové with histologically confirmed clinical diagnosis of oral lichen planus in the period 2003 – 2013. The data were retrospectively reviewed. Results: Of the 171 patients, 116 (67.8%) were women and 55 (32.2%) were men. The mean age was 55.2 ± 12.4 years (range of 85.0 – 20.9). The reticular form was the most frequent 93.6% (160 pts.), desquamative gingivitis was 12.9% (22). The buccal mucosa was the site most affected 89.5% (153 pts.). The lesions were asymptomatic in 52 patients (30.4%). Extraoral lesions were observed in 20.5% (35 pts.) of the patients, skin involvement was in 16.4% (28 pts.). Smokers were 29 patients. Local treatment used 116 (67.8%), only 6 patients used systemic short tome corticoid therapy. No evidence between OLP and malignant transformation was observed. Conclusions: This retrospective study show very similar profile and clinical features of the patients with OLP as in other studies. Key words:Oral lichen planus, clinical features, extraoral manifestation.

Clinicopathological profile and malignant transformation in oral lichen planus: A retrospective study

“…[34581516] Unilateral occurrence of lichen planus was observed in few of our cases, which clinically mimics another condition known as lichenoid reaction. Although they also show few similarities histopathologically, lichenoid reaction can be differentiated from lichen planus on the basis of subepithelial as well as diffuse infiltration of inflammatory infiltrate with substantial numbers of plasma cells, eosinophils, and neutrophils in contrast to only a subepithelial band of lymphocytes in the latter.…”

“…[34581617] However, Irani et al . reported erosive form to be the most common type in Iranian population.…”

“…[5] Several antigen-specific and nonspecific inflammatory mechanisms have been put forward to explain the pathogenesis of disease; however, the exact mechanism remains unknown.…”

Association of Oral Lichen Planus with Autoimmune Diseases in A Northern Serbia Population: Matched Case-Control Study and Literature Review

“…Eleven of them had histological confirmation of all cases with distinguish between OLP and OLL [1,11,23,25,[27][28][29][30][31][32][33] and five presented with control group [11,13,24,25,27]. It can be noticed clear difference in reported coexistence of thyroid gland pathosis and OLP between Northern and Central European countries (Finland [11], Czech Republic [28] and Croatia [34]) and Southern Mediterranean countries (Italy [1,26] and Turkey [29]).…”

Efficacy of photodynamic therapy in the treatment of symptomatic oral lichen planus: A systematic review

“…Typically, it affects adults over the age of 30‐year‐old with a slight female predication . Although any mucosal site can be affected, the buccal mucosa is the most frequently affected site followed by tongue and gingiva . Based on clinical features, OLP is classified into 5 different clinical forms: reticular, atrophic, erosive, papular, and bullous .…”